Genofocus Co., Ltd.

Genofocus, Inc.

Eui Joong Kim

Jae Gu Pan

Taek Ho Yang

Jeong Hyun Kim

Do Young Yum

Ji Eun Kang

Soo Young Park

Eun Young Kim

Hye Rim Lee

Young-Jae Eu

Seung Hwan Park

Jung Hyun Kang

Jae Youl Choi

Hyun Do Kim

Su Jin Kim

Dong Beom Lee

Eun-Hye Park

Hyun-Do Kim

Chankyu Lee

Minchul Park

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory disease, which contains, as an active ingredient, aGF423 strain, a superoxide dismutase high-producingGF424 mutant strain, a superoxide dismutase (SOD) derived from one of these strains, or both the strain and the SOD. The superoxide dismutase derived from theGF423 strain (KCTC 13222BP), which is the active ingredient of the present invention, effectively suppresses or degrades reactive oxygen species, and thus has the effect of fundamentally preventing the causes of inflammatory bowel disease caused by reactive oxygen species. Therefore, the composition of the present invention may be developed into various products, including excellent drugs and health functional foods for preventing or treating inflammatory bowel disease.

Pharmaceutical composition for treating inflammatory bowel disease

The present invention relates to astrain that produces superoxide dismutase (SOD), and also relates to an antioxidant, anti-inflammatory pharmaceutical composition and a pharmaceutical composition and food composition for preventing or treating hyperlipidemia, which include a superoxide dismutase produced by thestrain. The compositions of the present invention exhibit excellent effects without causing side effects, and may thus be used as functional raw materials or products having an enhanced activity of preventing or treating inflammation, cancer or hyperlipidemia in the pharmaceutical drug, food, cosmetic and livestock fields.

GF423 strain, and composition for providing antioxidant and anti-inflammatory activities or preventing or treating hyperlipidemia, including polypeptide produced by the same

The present invention relates to a beta-galactosidase mutant having high transglycosylation activity and containing a C-terminal deletion, and the use thereof and more. More specifically, the present invention relates to a beta-galactosidase mutant having a C-terminal deletion, a gene encoding the same, a recombinant vector containing the gene, a recombinant microorganism transformed with the gene or the recombinant vector, and a method for producing the beta-galactosidase mutant using the recombinant microorganism. Using the high transglycosylation activity of the beta-galactosidase mutant containing the C-terminal deletion according to the present invention, galactooligosaccharide can be efficiently produced in large amounts.

Beta-galactosidase variant having high transglycosylation activity, and use thereof

The present invention relates to a novel alpha-1,3-glucanase, and more particularly, to a novel alpha-1,3-glucanase from, a gene encoding the same, a recombinant vector and recombinant microorganism comprising the gene, and a method of producing an alpha-1,3-glucanase using the recombinant microorganism. The novel alpha-1,3-glucanase according to the present invention can effectively degrade mutan, which is a component of a microbial biofilm, and thus it can be used in oral hygiene products and the medical field.

Genes encoding alpha-1,3-glucanase and methods of using the same

The present invention relates to a novel beta-galactosidase, and more particularly to a novel beta-galactosidase derived from, a gene encoding the beta-galactosidase, a recombinant vector and a recombinant microorganism, which contain the gene, a method for producing a beta-galactosidase using the recombinant microorganism, and a method for producing galactooligosaccharide using the beta-galactosidase. The use of the novel beta-galactosidase according to the present invention makes it possible to efficiently produce a large amount of galactooligosaccharide.

Beta-galactosidase

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Daejeon, South Korea

Eui Joong Kim