Hewlett-Packard Company

Eugene M Wong

James L Bertsch

Steven Michael Fischer

Darrell L Gourley

Robert G Nordman

Kent D Henry

The invention relates to an ionization chamber. More particularly, the invention relates to a mass spectrometer system having an electrospray ionization chamber incorporating an asymmetric electrode.

Ionization chamber and mass spectrometry system containing an asymmetric

An atmospheric pressure ionization source is provided which includes an ionization chamber that is formed from the combination of an angled chamber body and a correspondingly angled chamber seal. The ionization chamber is used for electrospray or atmospheric pressure chemical ionization of a liquid sample to provide ionized molecules. The ionized molecules can be passed to an associated analytical device that is capable of detecting and measuring the mass-to-charge ratio and/or the mass and charge of the molecules. A mass spectrometer which includes the present atmospheric pressure ionization source is also provided, as well as a liquid chromatography/mass spectrometry (LC/MS) analysis system which includes an LC/MS interface comprising the present atmospheric pressure ionization source.

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Campbell, CA, United States of America

Eugene M Wong