Janssen Pharmaceutica Nv

Ortho-mcneil Pharmaceutical Corp.

Other

Eugene B Grant

Mark J Macielag

Todd C Henninger

Dennis J Hlasta

Daniel T W Chu

Chaitin Khosla

Steven David Paget

Xiaoqing Xu

Michele Ann Weidner-Wells

Tianbao Lu

Gary W Ashley

Guozhang Xu

Micheal D Gaul

Xiaodong Xu

Deodialsingh Guiadeen

Tho V Thieu

Zhijie Liu

Boying Guo

Jing Zhang

The present invention is directed to pyridine N-oxide derivatives, stereoisomers, isotopologues, isotopomers and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing said compounds and the use of said compounds in the treatment and/or prophylaxis of thromboembolic disorders, inflammatory disorders and diseases or conditions in which plasma kallikrein activity is implicated.

Pyridine N-oxide derivatives useful as factor XIa inhibitors

The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R, R, R, R, R, A, E, X, Y, a and b are as defined above;or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.

7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

A non-gravity-type resistance exercise apparatus that includes a novel pulley-carrying exercise arm that can be incrementally rotated in a novel manner between high, low and numerous intermediate exercise positions to enable the proper performance of a number of different exercises. The apparatus includes a compact, self-contained, selectorized resistance module that embodies a plurality of discrete, elongated elastomeric cords that can be quickly and easily selectively coupled with the body-engaging means to provide precise resistance to the performance of several different kinds of exercises.

Exercise apparatus

6-O-carbamate-11,12-lacto-ketolide antimicrobials

Ketolide antibacterials

Growing community of inventors

Flemington, NJ, United States of America

Eugene B Grant