Other

Vanderbilt University

Eugene A LeBoeuf

John P Wikswo

William Hudson Hofmeister

Franz Baudenbacher

David Edward Cliffel

Lisa J McCawley

Frederick R Haselton

Ales Prokop

Leslie A Weaver

Mark Andrew Stremler

Randall S Reiserer

Charles P Lin

Chang Y Chung

A bioreactor for cultivating living cells in a liquid medium. In one embodiment of the present invention, the bioreactor includes a first substrate having a first surface, an opposite second surface and edges. The bioreactor further includes a second substrate having a first surface and an opposite second surface, defining a cavity with a bottom surface, where the bottom surface is located therebetween the first surface and the second surface. The first surface of the first substrate is received by the second surface of the second substrate to cover the cavity so as to form a channel for receiving cells and a liquid medium. In forming the bioreactor, the channel is sized to allow the growth of a layer of cells on a biocompatible coating layer and a flow of liquid in the channel. The flow of liquid is controlled so as to provide a known shear force to the layer of cells. The flow of liquid can be further controlled so as to provide an environment that simulates a vascular space in the channel.

Capillary perfused bioreactors with multiple chambers

A tractor drawn lift bed highway trailer for transporting high tonnage loads over the highway, utilizing pallet frame units adapted to be picked up or dropped off quickly without the need for additional equipment or personnel. The trailer has a relatively light, strong main frame; a lift bed adapted to be elevated from lowered loading position forwardly and upwardly into engagement with the gooseneck for additional rigidity during transport; improved protection for the load and the tractor in event of an emergency stop; and improved cornering characteristics.

Lift bed pallet highway trailer

A lift bed highway trailer adapted to be coupled to a tractor to transport heavy loads through use of pallet frame units that can be quickly picked up and discharged at any point, wherein provision is made in the trailer gooseneck structure for safely dissipating the kinetic energy of the pallet frame unit through resistance of friction and gravity in event of an emergency stop.

Trailer deflector ramp

Growing community of inventors

Noblesville, IN, United States of America

Eugene A LeBoeuf