Merck Patent Gmbh

Merck Patent Gesellschaft MIT Beschrankter Haftung

Merck Patent Gesellschaft MIT Beschraenkter Haftung

Eugen Merkul

Dieter Dorsch

Thomas J J Mueller

Christian Sirrenberg

Margarita Wucherer-Plietker

Gnuni Karapetyan

Thomas J Mueller

Thomas Jj Mueller

Lars Thore Burgdorf

Christina Esdar

Thomas Mueller

Christian Sirenberg

Gnuni Amatunu Karapetyan

Margarita Wuchrer

Margarita Wucherer-plietker

Thomas JJ Mueller

Compounds of the formula (I) in which R, R, Rand Rhave the meanings indicated in Claim, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.

7-azaindole derivatives

Compounds of the formula (I), in which R, R, Rand Rhave the meanings indicated in Claim, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.

5-(1,2,3-triazol-4-yl)-7H-pyrrolo[2,3-D]pyrimidine derivatives

Compounds of the formula (I) in which R, R, Rand Rhave the meanings indicated in claim 1, are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.

The invention relates to compounds the formula (I): and pharmaceutically usable salts, tautomers and stereoisomers thereof, wherein R, Rand Rare defined herein. The compounds of formula (I) and their pharmaceutically usable salts, tautomers and stereoisomers are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.

Substituted 7-(1,2,3-Triazol-4-yl)-pyrrolo[2,3-b]pyrazines

Compounds of the formula (I), in which R, R, R, Rand Rhave the meanings indicated in Claim, are inhibitors of cell proliferation\cell vitality and can be employed for the treatment of tumors.

4 (pyrrolopyridinyl)pyrimidin-2-ylamine derivatives

Compounds of the formula (I), in which R, R, Rand Rhave the meanings indicated in claim (), are inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumors. 

6-(pyrrolopyridinyl) pyrimidin-2-ylamine derivatives and the use thereof for the treatment of cancer and AIDS

Compounds of the formula (I), in which R, Rand Rhave the meanings indicated in claim (), are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed for the treatment of tumors.

3-(1,2,3-triazol-4-yl) pyrrolo [2,3-b] pyridine derivatives

Compounds of the formula (I), in which R, R, R, Rand Rhave the meanings indicated in claimare inhibitors of cell proliferation/cell vitality and can be employed for the treatment of tumors.

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Duesseldorf, Germany

Eugen Merkul