Takeda Chemical Industries, Inc.

Senju Pharmaceutical Co., Ltd.

Amato Pharmaceutical Products, Ltd.

Etsunosuke Noda

Hiroshi Fujisawa

Kenzo Ishizuka

Kenichi Yoshida

Akihiro Nagai

Yoshiharu Matukura

A therapeutic agent for hemorrhoidal diseases, comprising, as an active ingredient, a diester phosphate compound of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and each is a hydrogen atom or a methyl, or a pharmacologically acceptable salt thereof, and a method for treating hemorrhoidal diseases, comprising administering a pharmaceutically effective amount of said diester phosphate compound or a pharmacologically acceptable salt thereof.

Therapeutic agent for hemorrhoidal diseases

The present invention relates to a stabilized aqueous suspension of oxendolone, which contains 0.05 to 1.0 w/v percent of a nonionic surfactant and 0.01 to 0.25 w/v percent of a p-hydroxybenzoic acid ester. The suspension satisfy the requirements of a pharmaceutical preparation and shows a prolonged activities of oxendolone without accompanying pain when it is injected.

Aqueous suspension of oxendolone

Solid antibiotic compositions containing 7.beta.-[2-(2-imino-4-thiazolin-4-yl)acetamido]-3-{1-[2-(N,N-dimethylamino )-ethyl]-1H-tetrazol-5-yl}thiomethyl-3-cephem-4-carboxylic acid dihydrochloride or its hydrate and a pharmaceutically acceptable carbonic acid salt are rapidly converted into an injectable solutions by the addition of a solvent, and the injectable solution shows high antibacterial activity with less local reactions when injected.

Antibiotic compositions

Solid antibiotic compositions containing 7.beta.-[2-(2-imino-4-thiazolin-4-yl)acetamido]-3-{1-[2-(N,N-dimethylamino )ethyl]-1H-tetrazol-5-yl}thiomethyl-3-cephem-4-carboxylic acid dihydrochloride or its hydrate and a pharmaceutically acceptable carbonic acid salt are rapidly converted into an injectable solutions by the addition of a solvent, and the injectable solution shows high antibacterial activity with less local reactions when injected.

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Yao, Japan

Etsunosuke Noda