L'oreal

I.b.r. Israeli Biotechnology Research Ltd.

Israeli Biotechnology Research Ltd.

Etienne Soudant

Inon Perry

Lea Bezalel

Jean-Francois Nadaud

Meira Ziv

Roland M Bazin

Aviv Shaish

Ami Ben-Amotz

Hedva Schickler

Judith Paltiel

Jean-Pierre Laugier

Constantin Koulbanis

Yuki Hata

Louis L Marcotte

Gerard Obadia

Fabien Havas

Olga Ben-Chitrit

Ilana Kachko-Chernetsky

Patrick Trannois

Lea Von Oppen-Bezalel

Lan Quang N'Guyen

Alex Aliluiko

Liki Von Oppen Bezalel

Fumio Maniwa

Akemi Takayama

Fishbein Manor Danit

Iliana Kachko-Chernetsky

Danit Fishbein Manor

The present invention provides compositions comprising extracts of Jojoba () in a polar solvent that are effective in promoting the barrier functions of the skin, useful for improving skin integrity, health and appearance and as anti-aging agent.

Jojoba extract useful in improving skin barrier functions

The present invention relates to use of carotenoid preparations for promoting skin whitening. Particularly, the present invention discloses that a combination of phytoene and phytofluene is effective in whitening skin. The present invention further relates to carotenoid compositions comprising a combination of phytofluene and phytofluene effective in whitening skin and at least one additional carotenoid, particularly carotenoids devoid of highly intense color.

Carotenoid compositions useful for whitening skin

A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.

Carotenoid preparation

A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.

Methods of inhibiting proliferation of cells

Anti proliferative preparations

A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation. A preferred dormant preparation is prepared from a water extract of Narcissus (daffodil) bulb.

Anti-proliferative preparations

The invention relates to a treatment and/or prevention of the problems of adiposity, with the aim being to obtain a cosmetic and/or therapeutic slimming effect which is generalized or localized on the human or animal body, the said process being characterized in that it consists in administering to the body, preferably via the topical route, at least one substance capable of limiting or of inhibiting the uptake of glucose by adipocytes. In addition, it is also possible to supply the body, preferably via the topical route, with at least one compound capable of stimulating lipolysis, the said supply being made in a simultaneous or separate manner or spread out over time relative to the step for administration of the glucose-uptake inhibitors. It also relate to various cosmetic, dermatological and/or medicinal compositions intended for implementation of the said process, as well as to their various uses.

Process for combating adiposity and compositions which may be used for

The invention relates to a cosmetic or dermatological composition with controlled release of active principle containing at least photoconvertible carotenoid, capable of being converted to retinol and retinoic acid or its isomers, of following formula (I): ##STR1## in which the R.sub.1 and R.sub.2 substituents denote one of the following groups: ##STR2## at least one of the R.sub.1 and R.sub.2 substituents denoting a .beta.-ionone group of formula (II), the R.sub.3 and R.sub.4 substituents denoting hydrogen, a hydroxyl, carboxyl or C.sub.1 -C.sub.4 alkoxy group or forming, with the carbon atom of the ring, a carbonyl group, in a cosmetically or dermatologically acceptable medium.

Cosmetic or dermatological composition with controlled release of active

A method for combatting cellulitis or reducing localized fatty excesses involves administering a body slimming amount of a composition which contains, as the sole slimming agent, an .alpha.-tocopherol, benzyl, xanthinol or hexyl nicotinate, or .alpha.-tocopherol acetate.

Method for combatting cellulitis or reducing localized fatty excesses

Use of a growth factor in a slimming composition

The use of lysine pyrrolidone carboxylate and arginine pyrrolidone carboxylate are disclosed as antioxidants in a cosmetic composition combined with at least one phenolic derivative.

Use of lysine pyrrolidone carboxylate and/or of arginine pyrrolidone

A cosmetic slimming composition for topical application to the skin contains in combination Ginkgo biloba as an alpha-2-blocker and at least one other alpha-2-blocker. This anti-cellulitis composition is capable of checking or stopping local fat accumulation and improving the esthetic appearance of the skin.

Slimming composition based on Ginkgo biloba as an alpha-2-blocker

An appliance for manual use for massaging a cutaneous covering, comprising, on the one hand, a reservoir (1) containing the product to be applied, and integral with a gripping element (2), the reservoir comprising a movable wall (4), so as to adapt its internal volume (9) to the quantity of product contained and, on the other hand, an applicator element (3) constituted by a sole (6) cooperating with the reservoir (1) and comprising at least one ball (7) held in a housing (8), which communicates with the internal volume of the reservoir (1) through at least one opening. The appliance also comprises a direct current source (12), which is situated in the said gripping element (2) and whose poles are each connected to one electrode, the first electrode (13) being a conductive covering which covers the wall of the gripping element (2) and the second electrode (14) being constituted by a conductive film which is in permanent contact with the product situated in the reservoir (1).

Massaging appliance

Growing community of inventors

Fresnes, France

Etienne Soudant