Neste Oy

Valtion Teknillinen Tutkimuskeskus

Optatech Corporation

Bioretec Oy

Bioretec Ltd

Bioasborbable Concepts, Ltd.

Suomen Putkisaneeraus Oy

Esa Suokas

Pertti Törmälä

Mikko Karttunen

Nureddin Ashammakhi

Erkki Laiho

Mika Harkonen

Mikko Hupa

Marja Ora

Mika H&auml;rk&ouml;nen

Seppo Kuusela

Seppo Makela

Heimo Ylänen

Jyri Koort

Minna Veiranto

Hannu Aro

Pertti T&ouml;rm&auml;la

Seppo Jarvinen

Porous bioabsorbable, bioactive and load-bearing composite medical device structure includes a plurality of regular textile planar layers (. . . ) formed of continuous bioabsorbable polymer matrix and bioceramic fibers acting as reinforcements, both included in continuous fibrous elements () forming the textile layers. The layers are placed on top of each other to form a structure having two dimensions (x, y) at right angles to each other according to the two dimensions of the textile layer and a third dimension (z) perpendicular to them and resulting from the piling of the layers. A plurality of passages extend through the layers as a result of the openings () defined by portions of the continuous fibrous elements () extending substantially in the direction of the plane. The continuous fibrous elements () comprise both bioactive ceramic reinforcing fibers which form a reinforcing structure and a bioabsorbable polymer matrix material which forms a matrix which binds the layers together and also binds the portions of continuous fibers defining the openings together, thereby forming the passages and stiffening the structure. This bioactive and bioabsorbable composite structure is suitable to be used as a basic structure in medical devices, especially in osteochondral applications where the load-bearing properties of implant are required.

Porous medical device and method for its manufacture

A method of enhancing the drug release rate from a composite material. The composite material includes a synthetic, bioabsorbable polymer matrix and a drug particle phase dispersed therein. The release rate of the drug from the polymer matrix is enhanced by orienting the composite material. The drug release rate of the oriented composite material is greater than the drug release rate from an otherwise comparable non-oriented composite material.

Method to enhance drug release from a drug-releasing material

This invention relates to bioabsorbable materials and implants used to prevent and treat infection and promote bone growth. More specifically, this invention relates to synthetic bioabsorbable drug delivery materials and implants comprising: (a) a synthetic bioabsorbable polymeric matrix; (b) an antibiotic phase dispersed into said polymeric matrix; and (c) antibacterial, bioabsorbable, bioactive glass, dispersed into said polymeric matrix for the promotion of bone growth.

Bioabsorbable drug delivery system for local treatment and prevention of infections

The present invention concerns a multilayered polymer film structure, which comprises at least one first layer (,) containing a thermoplastic polymer and at least one second layer (,), arranged adjacent to said first layer, containing a liquid crystalline polymer. According to the invention, the second layer (,) consists essentially of a compounded polymer blend formed by the liquid crystalline polymer and a thermoplastic polymer, the liquid crystalline polymer of the second layer forms a continuous phase, and the first and the second layers (,) contain the same thermoplastic polymer. The oxygen transmission rate of the second layer is less than about 150 cm,/(m,&middot;d&middot;bar), determined according to the standard ASTM D 3985-81, and the water vapour transmission rate of the integral film structure is less than 10 g/(m,&middot;24&middot;h) at RH 80% 23&deg; C., determined according to ASTM F 1249-90. The present structure can be used as a barrier layer in packages.

Multilayered polymer films and process for the preparation thereof

Polymer films and process for the preparation thereof

A planar porous composite structure including a plurality of regular textile planar layers formed of continuous yarns. The layers are placed on top of each other to form a structure having two dimensions at right angles to each other and a third dimension perpendicular to them and defining a plane having a direction along the two dimensions. A plurality of openings extends through the layers. Each opening is defined by portions of the continuous yarns extending substantially in the direction of the plane and existing in the regular textile planar layers to make the planar layers regular in structure prior to placing them on top of each other. A plurality of passages extends entirely through the structure in a direction substantially perpendicular to the plane of the structure. The continuous yarns comprise both reinforcing fibers which form a reinforcing structure and a matrix material which forms a matrix which binds the layers together and also binds the portions of continuous yarns defining the openings together, thereby forming the passages and stiffening the structure.

Planar porous composite structure and method for its manufacture

A method for repairing flow conduits, such as pipe lines, wherein the inner surface of a conduit is provided with a flexible material, including a curing agent as well as a reinforcement layer, and the curing agent is hardened, the reinforcement layer comprising a knitted fabric, wherein the knitted fabric comprises reinforcement filaments which are separate from a fabric-forming yarn and extend inside the knitted fabric substantially in a single direction.

Method for repairing flow conduits, and repair material

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Tampere, Finland

Esa Suokas