Idexx Laboratories, Inc.

Idexx Corporation

Erwin F Workman, Jr

Quentin J Tonelli

Mark Weston Pierson

Scott Marshall Clark

Ali Naqui

Robert H Suva

Haoyi Gu

Stanislaw Barski

Michael Raymond Kepron

Paul C Brooks

Invention performs an assay to determine presence or quantity of specific analyte in fluid sample. Representative device has two separate flow paths established sequentially in device with a single user activation step. First flow path delivers sample, and conjugate soluble binding reagents to solid phase. If analyte is present, an analyte:conjugate complex is formed and immobilized. Sample volume delivered by first path determined by absorbent capacity of solid phase, and not by amount of sample added to device. User need not measure sample volume. Sample/conjugate mixture is prevented from entering second flow path because capillary and surface energy of second flow path prevent it from being wetted by this mixture. Second flow path allows wash reagent to remove unbound conjugate and sample from solid phase to the absorbant, and optionally deliver detection reagents. Adaptable for many formats including, sandwich immunoassays, colloidal gold, sol particle, heterogeneous generic capture, and competitive assays.

Device and method for integrated diagnostics with multiple independent flow paths

Self-contained incubator for growth of microorganism

Disclosed is a dipstick test device for detecting an analyte in a liquid sample by treating the analyte with at least one liquid reagent to form a detectable reaction product. The device includes: a) an aqueous impermeable, aqueous insoluble reaction zone, adapted to retain the detectable reaction product; and b) a control absorbent above, and in liquid-transferring relation with, the reaction zone. The control absorbent has a predetermined, limited liquid-absorbing capacity, and the dipstick is sized and configured for insertion into a vessel containing the sample, with the control absorbent oriented above the reaction zone, so that the control absorbent fills to capacity with sample and the reaction zone incubates with the sample. The device may further include an absorbent reservoir which can be moved into liquid transferring contact with the reaction zone.

Dipstick test device including a removable filter assembly

Growing community of inventors

Cape Elizabeth, ME, United States of America

Erwin F Workman, Jr