Novartis Ag

Ernst Küsters

Michael Mutz

Gottfried Sedelmeier

Thomas Schupp

Ulrich Meier

Frank Stowasser

Daniel Kaufmann

Hans Hofmann

Lukas Oberer

Andreas Meyer

Frank Petersen

Marion Mahnke

Klaus Memmert

Nabila Sekkat

Michael Ambühl

Heinz Unternährer

Corine Gessier-Vial

Christa Hartmann

Peter Koch

Disclosed are compounds of formula I wherein R, R, Rand Rare as defined in the claims; such compounds have interesting pharmacological properties.

Aminoalkanol derivatives

The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.

Manufacture process

The invention relates to new crystal forms of epothilone B.

Crystal form of epothilone B and use in pharmaceutical compositions

A method of using an ionic liquid as solvent in headspace gas chromatography.

Ionic liquids as solvents in headspace gas chromatography

The invention relates to a new process for concentrating epothilones in culture media, a new process for the production of epothilones, a new process for separating epothilones A and B and a new strain obtained by mutagenesis for the production of epothilones, as well as aspects related thereto. New crystal forms of epothilone B are also described.

Fermentative preparation process for and crystal forms of cytostatics

The invention relates to a desorption process for epothilones, especially epothilone A and/or epothilone B, from resins and new production, work-up or purification processes or manufacturing methods for epothilones comprising said desorption process, as well as the use of certain solvents for the desorption of epothilones from resins.

Process for the isolation and purification of epothilones

Growing community of inventors

Eschbach, Germany

Ernst Küsters