Boehringer Ingelheim International Gmbh

Avir Green Hills Biotechnology Research Devlopment Trade Ag

Ernst Küchler

Thomas Muster

Ingrid Maurer-Fogy

Andreas Grassauer

Dieter Blaas

Andreas Zophel

Wolfgang Sommergruber

Timothy Skern

Horst Johann Ahorn

Hans-Dieter Liebig

Elisabeth Gaudernak

Joachim Seipelt

The invention discloses a use of dithiocarbamate compounds having the structural formula RRNCSH, in which Rand R, independently of each other, represent a straight or branched C-Calkyl, or, with the nitrogen atom, form an aliphatic ring with 4 to 6 C atoms, in which R, R, or the aliphatic ring is optionally substituted with one or more substituents selected from OH, NO, NH, COOH, SH, F, Cl, Br, I, methyl or ethyl, and oxidized forms of these compounds, in particular dimers thereof, as well as pharmaceutically acceptable salts thereof, to prepare an agent for treating or preventing an infection by RNA viruses which attack the respiratory tract and cause disease there.

Dithiocarbamate antiviral agents and methods of using same

The invention relates to the expression of mature HRV proteinase 2A, the partial purification thereof and the preparation of substrates having an inhibitory effect.

Expression of mature proteinase 2A, the partial purification thereof and

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Vienna, Austria

Ernst Küchler