Basf Aktiengesellschaft

Knoll Aktiengesellschaft

Ernst Flaig

Hartmut Hibst

Klaus Harth

Thomas Moest

Reinhard Spengler

Helmut Fricke

Juergen Dembowski

A novel delayed-release form for pharmaceutical active compounds, characterized by a core containing the active compound and a diffusion-inhibiting, adhesive coating layer having a thickness in the range from 0.01 to 10 .mu.m, consisting of a chemical network which has been applied to the support in a plasma-assisted chemical deposition process, and a process for its production are described.

Delayed-release form for pharmaceutical active compounds

A solid drug form containing not less than 90% by weight verapamil is produced by granulating at from 30.degree. to 55.degree. C. with a little water, drying and, where appropriate, conventional tableting or by pelleting, in which case the granules obtained as described are, after cooling, moistened once again and compacted in a granulating mixer at from 30.degree. to 55.degree. C. and are dried.

Solid drug form with a high verapamil content

Growing community of inventors

Heidelberg, Germany

Ernst Flaig