Hitachi-high-technologies Corporation

Ernoe Pretsch

Michihiro Saito

This invention provides: a compound represented by formula (I):R&#x2014;Y&#x2014;(&#x2014;X-Phe-COCHCOCF)&#x2003;&#x2003;(I)wherein R denotes hydrogen, alkyl, phenyl, or a group capable of binding to a protein, peptide, amino acid, nucleic acid, or nucleotide; Y denotes CH, a carbocyclic ring, or a heterocyclic ring; X denotes O, S, NH, CH, OCH, CONH, or NHCO; Phe denotes phenylene; n is an integer between 1 and 5; and m is 1, 2, or 3. This inventions also provides a luminous complex of such compound and a rare earth ion, a labeling reagent comprising such compound or luminous complex, and a process for labeling a protein, peptide, amino acid, nucleic acid, or nucleotide using such labeling reagent.

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Uetikon am See, Switzerland

Ernoe Pretsch