The University of Tennessee Research Foundation

University of Memphis Research Foundation

US Government as Represented by the Secretary of the Army

Erno Lindner

Edward Chaum

Jidong Guo

Kenneth C Curley

The invention relates to a method for the controlled delivery of a drug as a function of bioavailable drug concentration, a sensor device for detecting bioavailable drug concentration, and a delivery device that controls delivery of the drug based on the real-time detection of bioavailable drug concentration.

Method and device for detection of bioavailable drug concentration in a fluid sample

The present invention is directed to an electrochemical sensor involving an electrode and a coating that surrounds the electrode, the coating comprising a structural component, a water immiscible solvent, a resistance decreasing component, and an ion exchange component, wherein the coating selectively partitions an electrochemically active drug from a fluid or vapor sample whereby an electrochemical signal within the coating can be measured using the electrode. Devices and methods for using this electrochemical sensor are also disclosed.

Growing community of inventors

Germantown, TN, United States of America

Erno Lindner