Shell Oil Comapny

Ernest R Freitas

Thomas H Colby

William R Durland

An improved process is disclosed for the preparation of 2-chloro-4-ethylamino-6-isopropylamino-s-triazine wherein two of the three chlorine atoms on cyanuric chloride are replaced with ispropylamino and ethylamino substituents by sequential reaction of cyanuric chloride in a mixed acetone/water solvent system with isopropylamine and ethylamine, respectively, in the presence of an alkali metal hydroxide acid acceptor. In this improved process, the formation of undesired 2-chloro-4,6-bis(ethylamino)- and 2-chloro-4,6-bis(isopropylamino)-s-triazine impuritiesis minimized by carrying out the initial chloride replacement reaction with an excess of cyanuric chloride over the stoichiometric amount and subsequently treating the reaction product from this initial chlorine replacement reaction with sufficient base to convert the unreacted cyanuric chloride to a water soluble basic salt of monohydroxydichloro-s-triazine followed, optionally and preferably, by phase separation of the aqueous solvent phase to remove at least a portion of the basic salt of monohydroxydichloro-s-triazine from the reaction mixture prior to the second chlorine replacement reaction.

Growing community of inventors

Houston, TX, United States of America

Ernest R Freitas