Medtronic, Inc.

American Hospital Supply Corporation

Arbor Surgical Technologies, Inc.

Baxter International Inc.

Baxter Travenol Laboratories, Inc.

Carbomedics Inc.

Autogenics

Other

Ernest Lane

Michael J Drews

Donnell William Gurskis

Alain F Carpentier

Shouyan Lee

Charles Huang

Thomas J Fogarty

Neil D Holmgren

David Tompkins

David Hemsley

Steven Robert Bacich

Takashi Harry Ino

Federico Gutierrez

Oleg Svanidze

Victor E Koik

Federico Guiterrez

Hung L Lam

A heart valve assembly includes an annular prosthesis and a valve prosthesis. The annular prosthesis includes an annular ring for dilating tissue within a biological annulus and a conformable sewing cuff extending radially from the annular member. The valve prosthesis includes a frame and a valve component. The annular ring is introduced into the biological annulus to dilate tissue surrounding the biological annulus and the sewing cuff conforms to tissue above the biological annulus. Fasteners are directed through the sewing cuff to secure the annular prosthesis to the biological annulus. The annular prosthesis may include a baleen element for biasing fabric on the annular ring outwardly to enhance sealing against the biological annulus. A valve prosthesis is then advanced into the sinus cavity, and secured relative to the annular prosthesis. The sewing cuff may enhance a seal between the valve prosthesis and annular prosthesis.

Conformable prostheses for implanting two-piece heart valves and methods for using them

Devices for fixturing a prosthesis to a first mass and methods of making and using the same are disclosed. Complementary fixturing devices and methods of making and using the same are also disclosed. The devices can be used to attach a heart valve gasket body to a biological annulus.

Methods of using a prosthesis fixturing device

A prosthetic heart valve assembly includes a gasket member and a valve member including a plurality of fasteners and a plurality of engagement members corresponding to the fasteners. The fasteners and/or engagement members may be configured to guide the engagement members into engagement with the fasteners. For example, the fasteners may include U-shaped spring-biased clips, e.g., attached to a core or other portion of a sewing cuff of the gasket member, and the engagement members may include latches or barbed protrusions that engage one or more holes in the fasteners. During use, the gasket member is introduced into a tissue annulus, and secured to the annulus, e.g., using a plurality of clips directed through the sewing cuff. The valve member is then introduced into the annulus and the engagement members are snapped or otherwise guided into engagement with the fasteners to secure the valve member relative to the gasket member.

Two-piece prosthetic valves with snap-in connection and methods for use

A heart valve assembly includes a prosthesis and a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus. The prosthesis includes an annular member, a flexible core at least partially defining a sewing cuff extending radially outwardly from the annular member, a rail ring disposed between the flexible core and the annular member, and a plurality of guide rails extending from the rail ring through respective openings in the flexible core. A fabric covering covers the prosthesis, and the guide rails extend through respective openings in the fabric covering. The prosthetic valve includes a frame including receptacles for receiving respective guide rails. After implanting the prosthesis within a biological annulus, the prosthetic valve is advanced along the guide rails until retention elements on the guide rails engage the receptacles to secure the prosthetic valve relative to the prosthesis.

Connection systems for two piece prosthetic heart valve assemblies and methods for making and using them

A heart valve assembly includes a prosthesis for receiving a prosthetic valve to replace a preexisting natural or prosthetic heart valve within a biological annulus adjacent a sinus cavity. The prosthesis includes an annular member implantable within the biological annulus for contacting tissue surrounding the biological annulus to provide an opening through the biological annulus, a collar extending upwardly from the annular member, and a sewing cuff extending radially outwardly from the annular member and/or collar. Optionally, the annular member and/or collar may be resiliently compressible, expandable, and/or otherwise biased. A valve member, e.g., a mechanical or bioprosthetic valve may be coupled to the collar, e.g., using a drawstring, sutures, or other connectors, to secure the valve member to the gasket member.

Gasket with collar for prosthetic heart valves and methods for using them

A heart valve assembly including an annular prosthesis implantable within a biological annulus, a prosthetic valve including a multiple lobular shape for implantation above the biological annulus, and one or more connectors for securing the prosthetic valve to the annular prosthesis. A flexible sewing cuff extends radially from the annular prosthesis that is resiliently flexible for conforming to the multiple lobular shape of the prosthetic valve to enhance a seal between the prosthetic valve and the annular prosthesis. The sewing cuff may include a core resiliently conformable with anatomy surrounding the biological annulus and fabric covering at least a portion of the core.

Two piece heart valves including multiple lobe valves and methods for implanting them

A biologically implantable prosthesis is disclosed. The prosthesis can have a circumferentially expandable wall and elements that prevent the wall from collapsing once the wall is expanded. Methods of making and using the prosthesis are also disclosed.

Prosthesis heart valve fixturing device

A trileaflet biological prosthetic heart valve () comprising a thin, rigid annular outer frame () which supports three elastic, laminated spring inner frames () which in turn provide consistent geometric form and structure for attachment of tissue leaflets ().

Bioprosthetic heart valve

A heart valve prostheses includes an annular member implantable within a biological annulus, a collar extending upwardly from the annular member, and a sewing ring extending from the annular member. A spring structure couples the collar to the annular member and biases the collar to align with the annular member at a predetermined distance above the annular member. During use, the prosthesis is introduced into a biological annulus, and fasteners are directed through the sewing ring into surrounding tissue to secure the prosthesis with the annular member within the biological annulus. A mechanical or bioprosthetic valve is introduced and coupled to the collar, e.g., using tabs or other connectors on the collar. The spring structure allows the collar to be directed towards the annular member and/or folded inwardly, e.g., to facilitate accessing the sewing ring to deliver fasteners.

Growing community of inventors

Huntington Beach, CA, United States of America

Ernest Lane