Alliance Pharmaceutical Corp.

Pacira Pharmaceuticals, Inc.

Novartis Ag

Imcor Pharmaceutical Company

Nektar Therapeutics

Other

Inhale Therapeutic Systems, Inc.

Novartis Pharma Ag

Attenuex Technologies, Inc.

Solace Therapeutics, Inc.

Mokita Medical Gmbh

Ernest George Schutt

Jeffry G Weers

Thomas E Tarara

Luis A Dellamary

Alexey S Kabalnov

Charles David Anderson

David P Evitts

Kathleen D A Los

Ronald Warren McGuire

Peter Andrew Walters

Rene Alta Kinner

Jean G Riess

Peter L Dayton

Kevin Gerald Connors

John Gillespie, Jr

David H Klein

Leo A Trevino

Soroush M Ardekani

Louie Daniel Garcia

Mark H Wyzgala

Stephanie M Kurz

W Dean Kirkland

Mark A Walters

Vladimir Kharitonov

John K Hoffman

Katherine Stone

Kathleen Dunne Albright Los

Tilo Kölbel

Nicholas Simon Faithfull

Peter E Keipert

Adrian I Bot

Jean Reiss

Timothy J Pelura

Richard Gerard Vecchiotti

Alexev Kabalnov

Jeffrey G Weers

Kathleen DA Los

The present invention relates to a system for flushing a medical device, comprising a multi-port valve for controlling the delivery of flushing fluids, the multi-port valve connected to a source of pressurised flushing gas; a fluid outlet for coupling flushing fluids to the medical device; and, a gas-driven pump connected to the fluid outlet, wherein, in a first configuration, the multi-port valve couples a flow of gas from the source of pressurised flushing gas to the fluid outlet, and wherein, in a second configuration, the multi-port valve couples a flow of gas from the source of pressurised flushing gas to the gas-driven pump to drive the gas-driven pump thereby to provide a flow of flushing liquid to the fluid outlet.

Flushing devices and methods

Embodiments of the present disclosure are related to multivesicular liposome formulations encapsulating zinc meloxicam complex microparticles. Methods of making the zinc meloxicam complex microparticles and administering the zinc meloxicam complex microparticles encapsulated in multivesicular liposome formulations and their use as medicaments are also provided.

Zinc meloxicam complex microparticle multivesicular liposome formulations and processes for making the same

The present invention generally relates to the field of pharmaceutical sciences. More specifically, the present invention includes apparatus and devices for the preparation of pharmaceutical formulations containing large diameter synthetic membrane vesicles, such as multivesicular liposomes, methods for preparing such formulations, and the use of specific formulations for therapeutic treatment of subjects in need thereof. Formation and use of the pharmaceutical formulations containing large diameter synthetic membrane vesicles produced by using the apparatus and devices for therapeutic treatment of subjects in need thereof is also contemplated.

Method for formulating large diameter synthetic membrane vesicles

An implant delivery system can be configured to deliver an inflatable implant into a bladder via a urethra. The delivery system can comprise an elongate tubular body, an inflation tube and an implant decoupler. The tubular body can comprise a central lumen configured to hold an inflatable implant in an initial un-inflated state for delivery of the implant into the bladder. A method of use can include passing a distal tip of the elongate tubular body into the bladder. The implant can be inflated and released into the bladder.

Implant with high vapor pressure medium

A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 &#x3bc;m. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.

Pulmonary delivery particles comprising an active agent

An implant for use in a human or animal body can include a flexible housing with an outer wall and having a chamber therein. The implant can have at least one high vapor pressure medium within the chamber. The at least one high vapor pressure medium can have a combined vapor pressure equal to or greater than about the average value of the hydrostatic pressure of the implantation site plus the skin tension of the housing minus the gas tension of the dissolved gasses present at the implantation site.

Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature of the particle compared to particles without the polyvalent cation. The powders are hollow and porous and are preferably administered via inhalation.

Phospholipid-based powders for drug delivery

Growing community of inventors

San Diego, CA, United States of America

Ernest George Schutt