Jackson State University

Ernest B Izevbigie

The present invention provides for a novel anti-neoplastic pharmaceutical composition. Specifically, the present invention provides for phytochemotherapeutic compositions produced from aqueous extracts (and fractions thereof), derived fromleaves. These pharmaceutical compositions inhibit the growth of neoplastic cells, including human breast cancer cells. Furthermore, the instant invention provides for methods of producing the compositions and methods of using the compositions to inhibit the proliferation of neoplastic cells.

Phytochemotherapy for cancer

The present invention provides for a novel anti-neoplastic pharmaceutical composition. Specifically, the present invention provides for phytochemotherapeutic compositions produced from aqueous extracts (and fractions thereof), derived from leaves. These pharmaceutical compositions inhibit the growth of neoplastic cells, including human breast cancer cells. Furthermore, the instant invention provides for methods of producing the compositions and methods of using the compositions to inhibit the proliferation of neoplastic cells.

The present invention provides for novel methods for measuring the levels of cyclic adenosine monophosphate (cAMP) produced by cells. Notably, the methods provided do not require that the cell membranes be disrupted. Specifically, the present invention provides for a methods of detecting and quantifying cAMP extracellularly and for kits useful in employing these methods. Furthermore the present invention also provides for a method of isolating cAMP produced by cell culture.

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Flowood, MS, United States of America

Ernest B Izevbigie