Bioversys Ag

Melinta Therapeutics, Inc.

Rib-x Pharmaceuticals, Inc.

Pfizer Corporation

Melinta Subsidiary Corp.

Melinta Subsidary Corp.

Erin M Duffy

Ashoke Bhattacharjee

Zoltan F Kanyo

Joseph A Ippolito

Hardwin O'Dowd

Brian T Wimberly

Rongliang Lou

Marco DeVivo

Shili Chen

Andrea Marra

Yuanqing Tang

Sandra Sinishtaj

Jay J Farmer

Joseph M Salvino

Deping Wang

Adegboyega K Oyelere

Joel A Goldberg

Joyce A Sutcliffe

Yanming Du

Dane M Springer

Matthew H Scheideman

Timothy S McConnell

John N Abelson

Mary Theresa Didiuk

Ravi Shanker Garigipati

Yusheng Wu

Wan F Lau

Roberto Colon-Cruz

Wayne S McDonald

Vinay Thakur

Jacek G Martynow

Trudy Grossman

Wan Lau

Jacek G Martinow

Ik-Hyeon Paik

Somenath Chowdhury

Marco Devivo

Keith Arthur Johnson

Matthew Scheideman

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (A):

Substituted pyrrolo[2,3-d]pyrimidines as antimicrobials

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I):

Antimicrobial compounds and methods of making and using the same

The present disclosure relates to methods of treating, preventing, reducing the risk of, or delaying the onset of microbial infections in humans and animals that are caused by or involves one or more microorganisms which are capable of being used as biological weapons, the method including administering a pyrrolocytosine compound or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer.

Biodefense agents

The present disclosure relates generally to methods of treating infections in overweight or obese patients using antibiotics. According to statistics compiled by National Health and Nutrition Examination Survey conducted by the National Center for Health Statistics (NCHS) of the U.S. Centers for Disease Control and Prevention (CDC), in 2009-2010, 35.7% of adults in the United States were found to be obese. Ogden, C.L. NCHS Data Brief 2012, 82, available at http://www.cdc.gov/nchs/data/databiefs/db82.pdf (last visited Mar. 2, 2013).

Methods of treating infections in overweight and obese patients using antibiotics

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer

Antimicrobials methods of making and using the same

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

Antimicrobials and methods of making and using same

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I): or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.

The present disclosure relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals. In some embodiments, the present disclosure provides a compound of Formula (I) or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. 

The present invention relates to methods for treating acne and other skin infections caused or mediated by, orin a patient with a safe and effective amount of a topically applied oxazolidinone antibiotic compound.

Method for treating, preventing, or reducing the risk of skin infection

The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and/or reducing the risk of microbial infections in humans and animals.

The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, and reducing the risk of microbial infections in humans and animals.

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Deep River, CT, United States of America

Erin M Duffy