Pioneer Hi-Bred International, Inc.

E.i. Dupont De Nemours and Company

Cedars-Sinai Medical Center

Corteva Agriscience LLC

Erin L Crowgey

Joshua K Young

Cathy Xiaoyan Zhong

Albert Laurence Lu

Scott H Diehn

Christopher Jay Scelonge

James C Register, Iii

Timothy M Nowatzki

M Alejandra Pascual

Douglas S Nubel

David Hondred

Kent Brink

Nina Dietrich

Jennifer E Van Eyk

Douglas Stuart Nubel

Justyna Fert-Bober

Ronald Holewinski

Benjamin Phillip Berman

James Calvin Register

M Alejandra Villanelo

Iii James Calvin Register

M Alejandra Pascual Villanelo

The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.

Maize event DP-004114-3 and methods for detection thereof

Provided herein are methods and markers for diagnosing cardiovascular disease and/or neurodegenearative diseases in a subject. The methods include obtaining a biological sample from a subject in need of diagnosis and detecting the amount of a citrullinated protein or a citrullinated peptide in the biological sample obtained from said subject.

Role of citrullination in diagnosing diseases

Compositions and methods related to transgenic plants comprising seed production technology are provided. Specifically, maize plants having a E6611.32.1.38 event which confers seed production technology are provided. The plant harboring the E6611.32.1.38 event at the recited chromosomal location comprises the genomic/transgene junctions described. The plant genomic DNA flanking the integrated E6611.32.1.38 event can be used to design assays that will be specific for the E6611.32.1.38 event. The characterization of the genomic insertion site of the E6611.32.1.38 event provides for an enhanced breeding efficiency and enables the use of molecular markers to track the transgene insert in the breeding populations and progeny thereof. Various methods and compositions for the identification, detection, and use of the maize E6611.32.1.38 event are provided.

Plant genomic DNA flanking SPT event and methods for identifying SPT event

Growing community of inventors

Newark, DE, United States of America

Erin L Crowgey