Shiseido Company, Limited

Takeda Chemical Industries, Inc.

Nof Corporation

Shiseido Research Center

Eriko Takeoka

Takashi Ohmori

Tomiyuki Nanba

Hiroyuki Kakoki

Masahiro Tajima

Toshihiko Nakane

Tohru Okamoto

Yohei Hamano

Chika Hamada

Yosuke Nakazawa

Jun Suzuki

Reiji Miyahara

Toshio Yanaki

Masazumi Watanabe

Akira Matsuo

Yoshiharu Tsuji

Tsunao Magara

Ryuichi Takamoto

Masashi Ogou

Reji Miyahara

Eiko Sato

Tsutomu Souma

A skin external preparation includes a finely dispersed wax composition that is solid or semisolid at room temperature, a nonionic surfactant, an aqueous dispersion medium, and an ionic water-soluble thickener, and optionally further contains at least one of silicone oil and fluorinated oil which is liquid at room temperature, and the mass ratio of the nonionic surfactant to the wax being 1.0 or more, the particle size of the finely dispersed wax is 500 nm or less, and it substantially contains no ionic surfactants therein.

Skin external preparation comprising an aqueous dispersion of finely dispersed wax, nonionic surfactant, and ionic water-soluble thickener

A skin treatment composition of the present invention is an external composition for skin comprising an alkylene oxide derivative expressed by Formula (I):RO-[(AO)(EO)]&#x2014;R&#x2003;&#x2003;(I)wherein AO is an oxyalkylene group of Cor C; EO is an oxyethylene group; m and n are 1&#x2266;m&#x2266;70 and 1&#x2266;n&#x2266;70 respectively, wherein EO is 20&#x2dc;80% by weight with respect to a total of AO and EO; each of Rand Ris a hydrogen or a hydrocarbon group having C. The alkylene oxide derivative (I) has a moisturizing effect, a rough skin improving effect, a stickiness improving effect, and a transdermal absorption promoting effect. When a refreshing agent is used together therewith in the composition of the present invention, the refreshing effect lasts for a long time and it is excellent in feeling of use without skin stimulation.

Skin treatment composition

A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.

Method for measuring skin absorbability

A skin treatment composition of the present invention is an external composition for skin comprising an alkylene oxide derivative expressed by Formula (I):RO&#x2014;[(AO)(EO)]&#x2014;R&#x2003;&#x2003;(I)wherein AO is an oxyalkylene group of Cor C; EO is an oxyethylene group; m and n are 1&#x2266;m&#x2266;70 and 1&#x2266;n&#x2266;70 respectively, wherein EO is 20&#x2dc;80% by weight with respect to a total of AO and EO; each of Rand Ris a hydrogen or a hydrocarbon group having C. The alkylene oxide derivative (I) has a moisturizing effect, a rough skin improving effect, a stickiness improving effect, and a transdermal absorption promoting effect. When a refreshing agent is used together therewith in the composition of the present invention, the refreshing effect lasts for a long time and it is excellent in feeling of use without skin stimulation.

A hair growth phase extender containing, as an effective ingredient, at least one compound selected from the group consisting of unsaturated fatty acid and/or its derivatives, especially an unsaturated fatty acid having the formula:

Extract composition as hair growth phase extender

The invention relates to a hair revitalizing tonic composition containing, as an active ingredient, at least one lipid derivative of the general formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Y are as defined in the specification, and a and b are 0 or 1, as well as its use. Thus, there is provided a hair revitalizing tonic composition having an excellent hair loss prevention and hair revitalizing effect and, moreover, an excellent dandruff and itchy scalp prevention effect.

Hair revitalization tonic composition containing a lipid derivative and

Growing community of inventors

Yokohama, Japan

Eriko Takeoka