Daiichi Sankyo Company, Limited

Eriko Kioi

Yasuyuki Ogawa

Toru Taniguchi

Keiji Saito

Osamu Iwamoto

Katsuyoshi Nakajima

Kaori Ito

Nobuya Kurikawa

Shinji Tanaka

Kazumasa Aoki

Satoshi Shibuya

Wataru Saitoh

Natsumi Nishihama

Momoko Ogitani

Tsuyoshi Mikkaichi

Seiko Nagata

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: A: e.g., Benzene, E: e.g., —CH—, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R, R, R: e.g., a halogen atom, R: e.g., a C1-C6 alkyl group, R: e.g., a hydrogen atom, R, R, R, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, n, n, n: e.g., 1.

Compound having cyclic structure

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below: R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group; A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

Griseofulvin compound

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below:R: e.g., a C1-C6 alkyl group; R: a C1-C6 alkyl group;A: e.g., an oxygen atom; and R: e.g., a C1-C6 alkyl group.

An object of the present invention is to provide a compound having an anti-inflammatory activity or a pharmacologically acceptable salt thereof. The solution of the present invention is a compound of general formula (1) or a pharmacologically acceptable salt thereof. wherein the symbols in the formula are defined below:A: e.g., Benzene, E: e.g., &#x2014;CH&#x2014;, G: e.g., a 5-membered aromatic heterocyclic ring, X: e.g., cyclohexane, J: e.g., a 5-membered aromatic heterocyclic ring, Y: e.g., a phenyl group, R, R, R: e.g., a halogen atom, R: e.g., a C1-C6 alkyl group, R: e.g., a hydrogen atom, R, R, R, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, R: e.g., a hydrogen atom, n, n, n: e.g., 1.

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Yokohama, Japan

Eriko Kioi