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Merck Patent Gmbh

Erik W Wilker

Nancy C Wilker

Bayard R Huck

Remigiusz Kaleta

Andreas Machl

In a first aspect, the invention provides a sensorially attractive puncture-resistant panel having a first surface and a second surface, wherein at least one of the first surface and the second surface is sensorially attractive. In some embodiments, the panel comprises, consists, or consists essentially of a first layer having a first surface and a second surface, wherein at least one of the first surface and the second surface is sensorially attractive, and a second layer that is puncture-resistant and comprises, consists, or consists essentially of a puncture-resistant material. In some embodiments, the panel is sensorially attractive to a child.

Sensorially attractive puncture-resistant panel

The invention relates to combinations of 4-[(S)-2-Azetidin-1-yl-1-(4-chloro-3-trifluoromethyl-phenyl)-ethylamino]-quinazoline-8-carboxylic acid amide and/or its physiologically acceptable salts and solvates, and an inhibitor of Her2, and the use of such combinations for the treatment of cancer.

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Lexington, MA, United States of America

Erik W Wilker