Fei Comapny

Koninklijke Philips Corporation N.v.

Erik Rene Kieft

Michael Grass

Peter Christiaan Tiemeijer

Pavel Potocek

Pleun Dona

Bart Jozef Janssen

Bert Henning Freitag

Kun Liu

Erik Martinus Hubertus Petrus Van Dijk

Daniel Simon Anna Ruijters

Gerard Nicolaas Anne Van Veen

Sander Hans Denissen

Ali Mohammadi-Gheidari

Marco Verstege

Gerard Van Veen

Ondrej R Baco

Lukás Hübner

Dirk Dijkkamp

Jasper Frans Mathijs Van Rens

Maikel Hendriks

Wouter Verhoeven

Milos Hovorka

Peter Mutsaers

Jom Luiten

Walter Van Dijk

Jasper Van Rens

Petrus Mutsaers

Electron beam modulation in response to optical pump pulses applied to a sample is measured using SPAD elements. Individual detection events are used to form histograms of numbers of events in time bins associated with pump pulse timing. The histograms can be produced at a SPAD array, simplifying data transfer. In some examples, two SPAD arrays are stacked and a coincidence circuit discriminates signal events from noise events by determining corresponding events are detected within a predetermined time window.

Time-gated detection, dual-layer SPAD-based electron detection

Disclosed herein are radio frequency (RF) cavities and systems including such RF cavities. The RF cavities are characterized as having an insert with at least one sidewall coated with a material to prevent charge build up without affecting RF input power and that is heat and vacuum compatible. One example RF cavity includes a dielectric insert, the dielectric insert having an opening extending from one side of the dielectric insert to another to form a via, and a coating layer disposed on an inner surface of the dielectric insert, the inner surface facing the via, wherein the coating layer has a thickness and a resistivity, the thickness less than a thickness threshold, and the resistivity greater than a resistivity threshold, wherein the thickness and resistivity thresholds are based partly on operating parameters of the RF cavity.

Coating on dielectric insert of a resonant RF cavity

Methods and systems include acquiring instances of data relating to multiple layers of a sample obtained via slice and view imaging where the electron interaction depth of the charged particle beam during each irradiation of the sample is larger than the thickness of the first layer and/or the thickness of the second layer. A simulated model is then accessed that identifies a plurality of yield values that identify expected portions/ratios of detected emissions that are expected to be generated by material in corresponding layers/depths of the sample. The yield values are used to segregate the instances of data into component portions based on the particular layer of the sample in which the structures expected to have generated the associated emissions are located. The component portions are then used to create reconstructions of individual layers and/or 3D reconstructions of the sample with reduced depth blur.

Slice depth reconstruction of charged particle images using model simulation for improved generation of 3D sample images

Disclosed herein are systems and methods for pulsing electron beams and synchronizing the pulsed electron beam with scanning a sample at a plurality of scan locations. An example method at least includes pulsing an electron beam to form a pulsed electron beam having a pulse period, moving the pulsed electron beam to interact with a sample at a plurality of locations, the interaction at each of the plurality of locations occurring for a dwell time, and synchronizing data acquisition of the interaction of the pulsed electron beam with the sample based on the pulsing and the translating of the electron beam, wherein the dwell time is based on a derivative of the pulse period.

System and method for RF pulsed electron beam based STEM

The invention addresses the problem of correctly positioning a catheter and reducing radiation doses. It relates to an X-ray imaging system () for a robotic catheter, comprising said catheter (), and a processing unit () for receiving X-ray images of a patient environment (). By being adapted to receive one or more auxiliary information items and using said information for determining the catheter position, the processing unit does not entirely have to rely on a large number of scanned image data, thus helping to reduce radiation while correctly delivering the catheter position as a function of as few as a single image, preferably 2D, and said one auxiliary information items. Further, said processing unit allows for at least one of rendering an image and provide said image to a visualization device (), and providing feedback, e.g. steering commands, to said robotic catheter.

X-ray imaging system for a catheter

Charged particle beams (CPBs) are modulated using a beam blanker/deflector and an electrically pulsed extraction electrode in conjunction with a field emitter and a gun lens. With such modulation, CPBs can provide both pulsed and continuous mode operation as required for a particular application, while average CPB current is maintained within predetermined levels, such as levels that promote X-ray safe operation. Either the extraction electrode or the beam blanker/deflector can define CPB pulse width, CPB on/off ratio, or both.

Pulsed CFE electron source with fast blanker for ultrafast TEM applications

A multi-electron beam imaging apparatus is disclosed herein. An example apparatus at least includes an electron source for producing a precursor electron beam, an aperture plate comprising an array of apertures for producing an array of electron beams from said precursor electron beam, an electron beam column for directing said array of electron beams onto a specimen, where the electron beam column is configured to have a length less than 300 mm, and where the electron beam column comprises a single individual beam crossover plane in which each of said electron beams forms an intermediate image of said electron source, and a single common beam crossover plane in which the electron beams in the array cross each other.

Multi-electron-beam imaging apparatus with improved performance

An apparatus and a method are provided for controlling collimation operation of a collimator in an x-ray imager during an intervention carried out by an operator. A first medical device is made to progress through a patient in an exploratory phase of the intervention. A path is recorded in a scout image formed from footprints of the first device as recorded in a sequence of projection images acquired by imager during the exploratory phase. Apparatus uses the path in the scout image to control collimation of the x-ray beam during a subsequent delivery phase where a second medical is made to progress through patient, said second device following the first device substantially along the same path.

ROI painting

A time delay integration (TDI) sensor () comprises a sequence of cells () numbered 1 to N. The TDI sensor is configured for transferring a charge from the cell numbered 1 via the cells numbered 2 to N&#x2212;1 to the cell numbered N. Each cell () in the sequence of cells is either sensitive or insensitive in the sense that when the TDI sensor () is evenly illuminated by light () having a first spectrum, the intensity of the light () incident on any of the insensitive cells () is at most 90% of the intensity of the light () incident on any of the sensitive cells (). The sequence of cells () comprises, in this order: a first sensitive cell (), at least one insensitive cell (), and a second sensitive cell (). An imaging system comprising a TDI sensor and a method of imaging an object are also disclosed.

Time domain multiplexing for imaging using time delay and integration sensors

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Eindhoven, Netherlands

Erik Rene Kieft