Spf Technologies LLC

Erik O Blomquist

Gaston De Los Reyes

Barry Gaiman

Methods and devices are disclosed for a separation device. A separation device includes a plurality stacked modules and a distribution network including an inter-module LEVEL-1 distributor an intermediate LEVEL-2 distributor and a planar LEVEL-3 distributor. The distribution network enables streamline lengths which are approximately equal and induces uniform velocity fluid flow. These features provide a narrow residence time distribution providing improved chromatographic performance.

Separation module

Methods and devices are disclosed for a separation device. A separation device includes a separation module having a separation membrane separating an interior of the separation module into a retentate compartment and a permeate compartment. The retentate compartment includes at least one retentate channel, a feed port fluidly coupled to the at least one retentate channel and a retentate port. The permeate compartment includes at least one permeate channel disposed within the permeate compartment and a permeate port fluidly coupled to the at least one permeate channel. a retentate collector fluidly connected to the retentate port. The device further includes a feed reservoir, a permeate reservoir, a fluidic gate located between the feed reservoir and the separation module, a vent located between the retentate channel and the permeate channel end adjacent the retentate port and a pressure differential source applied across the separation module.

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Jamaica Plain, MA, United States of America

Erik O Blomquist