Cytiva Sweden Ab

Ge Healthcare Bio-sciences Ab

Erik Nils Ostlund

Hanno Ehring

Henrik Svanberg

Fredrik Lars Jarhede

The present invention relates to an optical flow cell for a measuring device, having an input light guide with a light exit surface, an output light guide with a light entrance surface, said input light guide and output light guide being integrated with a holder to form an optical flow cell, and wherein the holder extends along a first axis and has a through hole for receiving a flow of a sample fluid, said through hole being transversal to said first axis, and the input light guide and output light guide further are arranged in said holder so that the light exit surface and the light entrance surface extend into said through hole and are arranged to be in optical alignment with each other and at a first distance from each other. The invention also relates to a measuring device having at least one optical flow cell.

Optical flow cell for an optical measuring device

A measuring device for measuring the absorbance of a substance in at least one solution provided in at least two flow cells of the measuring device, wherein said measuring device comprises: &#x2014;a light source transmitting a first light ray; &#x2014;said at least two flow cells; &#x2014;an optical arrangement comprising at least two semi-transparent mirrors with different transmission properties, said optical arrangement being arranged for dividing the first light ray coming from the light source into separate light parts, one for passing each flow cell and one for entering directly after the optical arrangement a reference detector; and &#x2014;one detector provided after each flow cell for detecting light having passed through the flow cells.

Method and device for measuring absorbance of a substance in solution with multiple light rays

The present invention relates to an optical flow cell () for a measuring device, having an input light guide with a light exit surface, an output light guide with a light entrance surface, said input light guide and output light guide being integrated with a holder () to form optical flow cell (), and wherein the holder () extends along a first axis (A) and has a through hole () for receiving a flow of a sample fluid, said through hole () being transversal to said first axis (A), and the input light guide and output light guide further are arranged in said holder () so that the light exit surface and the light entrance surface extend into said through hole () and are arranged to be in optical alignment with each other and at a first distance from each other. The invention also relates to a measuring device having at least one optical flow cell ().

Disclosed is an apparatus for measuring the absorbance of a substance in a solution, comprising: i) a sample cell () of known path length (b) for containing said solution (S), said cell being transparent to light of a predefined wavelength spectrum; ii) plural LED's each being independently operable by means of a controller () each for emitting light, within said predefined wavelength spectrum, along a light path; iii) a band pass filter () in the light path; iv) a beam splitter () for dividing light from said source propagating along the path into a first portion and a second portion, said first portion being directable by the beam splitter toward a reference detector () and said second portion being directable into the cell (); v) a reference detector () for detecting the intensity of said first portion of light directed by said beam splitter; and vi) a sample detector () for detecting the intensity of the second portion propagating from the cell; the apparatus allowing a sample in the cell to be inexpensively subjected to more than one wavelength of light for quicker or more accurate analysis.

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Uppsala, Sweden

Erik Nils Ostlund