Medtronic Vascular, Inc.

Medtronic, Inc.

Pipeline Medical Technologies, Inc.

Boston Scientific Scimed, Inc.

Medtronic Ardian Luxembourg S.a.r.l.

Erik Griswold

Denise Marie Zarins

James Calvin Allan

Don H Tran

Gordon B Bishop

William Berthiaume

Trung Ho Pham

Cameron Paul Purcell

Stephen Riddle McDaniel

Randall T Lashinski

Steven Lawrence Waldhauser

Rudy Beasley

Justin Goshgarian

George Patras

Kamal Deep Mothilal

Jon D Schell

William John Havel

Padraig Savage

James D Reinke

Can Cinbis

Kevin M Mauch

David Jerome Peichel

Maria G Aboytes

Joshua J Dwork

Jonathan P Roberts

Michael Lee

Sean Ward

Finn Olavi Rinne

Mike Krivoruchko

John Kelly

Kendra Yasger

Gianfranco Pellegrini

William A Berthiaume

H Allan Steingisser

Brent L Locsin

Lance Ensign

Rudolph A Beasley

Suruchi Anand

Albert Harold Dunfee

Martha Barajas-Torres

Matthew Baldwin

Hien Ngoc Lam

Somboune Singkeo

Sean Miller

Fertac Bilge

Nathan K Brown

Robert J Beetel

Rui Lam

Richard Bliss

Vance E Swanson

Maria Valdovinos

Matthew S Poole

Arvind K Srinivas

Kris Kristoffersen

Kelly M Wien

Ronan Wood

Christopher Robert Lashinski

Giangranco Pellegrini

Kris Kristofferson

Arvind Srinivas

Jamie Dunaway

Stephen R Mcdaniel

Nathan Weimeyer

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Method and apparatus for mitral valve chord repair

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium, through the mitral valve, and into the left ventricle. A ventricular anchor is deployed from the catheter and into a wall of the left ventricle, leaving a ventricular suture attached to the ventricular anchor and extending proximally through the catheter. A leaflet anchor is deployed to secure a mitral valve leaflet to a leaflet suture, with the leaflet suture extending proximally through the catheter. The leaflet suture is secured to the ventricular suture to limit a range of travel of the leaflet in the direction of the left atrium. Also disclosed is an assembled in situ mitral valve leaflet restraint, having a neo papillary muscle and a neo chordae tendinea.

Method and apparatus for transvascular implantation of neo chordae tendinae

Methods and devices for transvascular prosthetic chordae tendinae implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, the catheter can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to a leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet connector carried by a distal end of the catheter can be anchored to a superior surface of a mitral valve leaflet. A needle is axially advanceable through the leaflet connector and through the leaflet. A leaflet anchor having a leaflet suture can be advanced out of the needle to secure the mitral valve leaflet to the leaflet suture. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Leaflet capture and anchor deployment system

Methods and devices for transvascular prosthetic chordae tendineae implantation are disclosed. A catheter is advanced into the left atrium. From an atrium side, a leaflet anchor having a leaflet suture is secured to the mitral valve leaflet. A ventricular anchor is anchored to the wall of the ventricle to secure the ventricular wall to a ventricle suture. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae. The suture lock has a body with a suture path extending therethrough. A wall in the housing is movable to reduce the cross section of the suture path. A drive mechanism advances the movable wall to clamp sutures extending through the suture path, in response to rotation of a coupling on the housing.

Endovascular suture lock

Features for a restraint, such as a cap, are described. The restraint secures a cardiac device in a collapsed, delivery configuration for transcatheter delivery to a heart. The restraint may have a tubular sidewall extending from a proximal end to a distal end, a proximal opening defined by the sidewall at the proximal end and a channel defined by the sidewall and extending distally from the proximal opening. The restraint is configured to receive the implant in the collapsed configuration through the proximal opening to radially restrain the implant within the channel. The restraint eliminates the need for a surrounding sheath, reducing the delivery profile and size of the overall delivery system, among other advantages. The restraint may have an atraumatic leading edge to reduce the risk of injury to the patient.

Deployment restraint and delivery system for implantable cardiac device

Method of securing a leaflet anchor to a mitral valve leaflet

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium to attach a leaflet anchor having a leaflet suture to a mitral valve leaflet. A ventricular anchor has a hub with a helical anchor and a core wire extending through the helical anchor. A radiopaque marker may be axially movably carried on the core wire, and a spring biases the marker in a distal direction. The marker is advanced proximally on the tissue surface relative to the helical anchor as the helical anchor is advanced distally into tissue to secure a ventricular suture to the ventricular wall. A leaflet suture and the ventricular suture may be tensioned and connected by a suture lock to form an artificial chordae.

Tissue anchor with dynamic depth indicator

Method of transvascular prosthetic chordae tendinae implantation

Methods and devices for transvascular prosthetic chordae tendinea implantation are disclosed. A catheter is advanced into the left atrium. A helical ventricular anchor subassembly is advanceable through the catheter, having a ventricular suture extending proximally through the catheter. A leaflet anchor subassembly is advanceable through the catheter, having a leaflet suture extending proximally through the catheter. From an atrium side, the leaflet anchor subassembly can be anchored to a superior surface of a mitral valve leaflet and a leaflet anchor can be advanced into the mitral valve leaflet to secure the mitral valve leaflet to the leaflet suture. The ventricular anchor subassembly secures the ventricular anchor to a ventricular wall. The leaflet suture and the ventricle suture may be tensioned and connected by a suture lock to form an artificial chordae.

Neo chordae tendinae deployment system

In one example, this disclosure is directed to a kit for intravascular implantation of an implantable medical device, the kit comprising an outer sheath, the outer sheath sized to traverse a vasculature of the patient, and an elongated inner sheath with a tapered distal end. The inner sheath is slidable within the inner lumen of the outer sheath and is selectably removable from the inner lumen of the outer sheath by sliding the inner sheath out of the proximal opening of the outer sheath. The kit includes an elongated deployment receptacle including a deployment bay slidable within the inner lumen of the outer sheath when the inner sheath is not within the inner lumen of the outer sheath. The deployment bay carries an implantable medical device through the inner lumen of the outer sheath and facilitates deployment of the implantable medical device from the distal end of the outer sheath.

Pass-through implantable medical device delivery catheter with removeable distal tip

An inner subassembly of a delivery system assembly extends within a lumen of an elongate outer tube of the assembly, and includes a flared distal end, which is preferably configured to conform to a proximal end of an implantable medical device; a distal-most portion of the outer tube is sized to contain both the flared distal end and an entirety of the medical device. The inner subassembly includes a core, an elongate pull-wire, extending along the core, and a sheath surrounding the pull-wire and the core; the sheath includes a slot opening that allows the pull-wire to pass laterally therethrough. The assembly preferably has a pre-formed curvature along a length of the sheath, and the slot opening extends along the pre-formed curvature. The outer tube is longitudinally moveable relative to the inner subassembly, for example, to deploy the medical device.

Delivery system assemblies for implantable medical devices

Growing community of inventors

Penngrove, CA, United States of America

Erik Griswold