Synarc Inc

Erik B Dam

Mads Nielsen

Claus Christiansen

Morten A Karsdal

Marleen De Bruijne

Arish Qazi

Jenny Folkesson

Paola Pettersen

Martin Lillholm

Dan Richter Jørgenson

Paola C Petterson

Ole F Olsen

Francois B Lauze

A statistical framework for identifying regions of discrimination between two groups of imaged objects involves determining a weight map defining the regions of discrimination by minimizing the sample size required to discriminate the two groups in a numerical optimization scheme.

Optimised region of interest selection

A method for the analysis of three dimensional scan data representing an articular cartilage is provided to extract a quantitative parameter indicative of joint pathology. A measure representative of cartilage homogeneity is derived from this three dimensional image data. The measured value is compared with similar measured values previously established in respect of healthy joints and/or joints characterised by a pathology.

Pathology indicating measure related to cartilage structure and automatic quantification thereof

A method for the analysis of three dimensional scan data representing an articular cartilage is provided to extract a quantitative parameter indicative of joint pathology. A measure of local curvature of the cartilage is determined within a region of interest. The value of the quantitative parameter of this joint derived from this measure is compared with the value of a similar quantitative parameter previously established in respect of healthy joints and/or joints characterized by a pathology.

Cartilage curvature

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Copenhagen, Denmark

Erik B Dam