Biochemie Gesellschaft M.b.h

Novartis Animal Health Us, Inc.

Sandoz Ag

Erich Zeisl

Paul Howard Ripley

Johannes Raneburger

David George Burch

Heinrich F Matous

Stefan Horkovics-Kovats

David George Sidney Burch

Described is a method for transdermally controlling a bacterial infection in a non-human animal which comprises the step of topically applying to the non-human animal a medicament comprising valnemulin in free base or a pharmaceutically acceptable salt form.

Use of pleuromutilin derivatives for transdermal treatment of bacterial diseases

Agglomerates of &bgr;-lactam antibiotics, such as penicilllin V potassium, amoxicillin trihydrate, cephalexin monohydrate, which are suitable for direct tablet formation.

Agglomerates of &bgr;-lactam antibiotics and processess for making agglomerates

Veterinary use of a pleuromutilin derivative

Complexes and pharmaceutical preparations containing complexes of the pleuromutilin derivative of formula I ##STR1## in free base or in acid addition or quaternary salt form and cyclodextrin are described. They can be prepared by complexing the above pleuromutilin compound with an appropriate cyclodextrin. They are indicated for use as pharmaceuticals, e.g. as antibiotics, especially in veterinary medicine, e.g. as feed additives.

Pleuromutilin derivative complexes

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Jenbach, Austria

Erich Zeisl