Dsm Fine Chemicals Austria Nfg Gmbh & Co. Kg

Hoffmann-la Roche Inc.

Dsm Fine Chemcials Nfg Gmbh & Co Kg

Erich Steinwender

Gerhard Steinbauer

Michael Stanek

Ernst Kupfer

Walter Raml

Curt Zimmermann

Stephan Doswald

Ernst Wressnegger

Georg Häubl

Georg Haubl

The invention relates to a method for alkylating cross-linked polymers containing N- or amino, ammonium or spiro-bicyclic ammonium groups. According to said method, the gelated polymers, obtained by polymerization and cross-linking, are a) optionally, deprotonated in water, an organic solvent or in a mixture of an organic solvent and water, by adding a base, b) optionally, washed once or more with water, an organic solvent or a mixture of an organic solvent and water, then c) one or more alkylators are added to the gel suspension which is stirred in water, an organic solvent or in a mixture of an organic solvent and water, at a temperature of between 5 and 160&#xb0; C. at normal or increased pressure, with a base being added after a short mixing time and d) reprotonation is carried out using a mineral acid, optionally after one or more washing steps, resulting in the alkylated, cross-linked polymers containing N- or amino, ammonium or spirobicyclic ammonium groups, accordingly.

Alkylation of crosslinked polymers containing N or amino or ammonium groups

Process for the drying of polymers containing N or amino, ammonium or spirobicyclic ammonium groups, comprising cationic N-containing groups, and suitable counterions, in which the gelled and washed polymers obtained by polymerization, crosslinkage and optionally alkylation are dried continuously using a gaseous medium under normal pressure or overpressure in a fluidized bed.

Process for the continuous drying of polymers containing N or amino, ammonium or spirobicyclic ammonium groups

An improved process for the preparation of substituted pyridinecarboxylic acids (II), useful as herbicide intermediates, by ozonolysis of quinolines (I).

Method for producing substituted pyridine-carboxylic acids

The present invention relates to a method for the purification of the lipstatin. Impurities are removed from a lipstatin preparation by: a) mixing the preparation with a polar phase and to form a first two phase system in which the ratio of the lipstatin to the non-polar impurities in the polar phase is greater than in the preparation, and separating the phases from the first two phase system and collecting the lipstatin-enriched polar phase, and b) i) diluting the lipstatin-enriched polar phase from step a) with water to form a diluted lipstatin-enriched polar phase containing the polar solvent in a percentage of at least seventy percent of the polar phase and lower than in the lipstatin-enriched polar phase from step a), and mixing the diluted lipstatin-enriched polar phase with a second non-polar phase, the second non-polar phase being the same non-polar solvent as the first non-polar phase in the same or greater relative amount to the polar phase as in the first two phase system; or ii) mixing the lipstatin-enriched polar phase from step a) with a second non-polar phase, the second non-polar phase being the same non-polar solvent as the first non-polar phase in a greater relative amount to the polar phase as in the first two phase system; to form a second two phase system in which the ratio of the lipstatin to the polar impurities in the second non-polar phase is greater than in the lipid-enriched polar phase from step a), and separating the phases from the second two phase system and collecting the lipstatin-enriched second non-polar phase.

Purification of lipstatin

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Linz, Austria

Erich Steinwender