Boehringer Mannheim Gmbh

Erich Fauland

Wolfgang Kampe

Max Thiel

Kurt Stach

Wolfgang Bartsch

Karl Dietmann

Harald Stork

Wolfgang Schaumann

Egon Roesch

Kurt Stach, Deceased

Uwe Bicker

Felix Helmut Schmidt

By Werner Plattner, Executor

Gottfried Hebold

Wolfgang Juhran

New amine derivatives of 4-hydroxy-2,1,3-benzthiadiazoles of the formula: ##STR1## wherein R is straight-chained or branched alkyl and the pharmacologically compatible salts thereof, that are markedly effected as inhibitors of adrenogenic .beta.-receptors and thus useful for the treatment and prophylaxis of cardiac and circulatory diseases.

4-Hydroxy-2,1,3-benzthiadiazole compounds and .beta.-adrenergic method

A 2-cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methane ##STR1## wherein R is a nitrile or carbamoyl group, and

2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes

Adenosine-5'-carboxylic acid derivatives of the general formula: ##STR1## wherein Z is two hydrogen atoms or a divalent lower alkylidene radical, ##STR2## R is an aliphatic or arylaliphatic radical, and R.sub.1 and R.sub.2 are independently a hydrogen, hydroxyl, amino, lower alkyl, lower alkenyl, optionally N-alkylated lower aminoalkyl, cycloalkyl, hydroxyalkyl or piperidinyl radical, or

Adenosine-5'-carboxylic acid amides

N(6)-disubstituted adenosine compounds of the formula: ##STR1## wherein R.sub.1 is alkenyl, cycloalkenyl or cycloalkenyl-alkyl; and

Therapeutic compositions and methods employing N(6)-disubstituted

New 4-hydroxy-benzimidazole compounds of the formula: ##EQU1## wherein R.sub.1 is straight-chained or branched alkyl and

4-Hydroxy-benzimidazole compounds and therapeutic compositions

New N(6)-disubstituted adenosine compound of the formula ##SPC1## Wherein

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Erich Fauland