Bayer Aktiengesellschaft

Bayer Intellectual Property Gmbh

Erich Brendel

Claus Weisemann

Ernst Chantraine

Roland Rupp

Venkata-Rangarao Kanikanti

Andreas Ohm

Alexander Kuhl

Adrian Funke

Michael Eisele

Patrick Bosch&eacute;

Stefan Kettelhoit

Frank Bröcker

Dennis Kvesic

Thomas Volkmer

Ranga-Rao Kanikanti

The present invention relates to a pharmaceutical dosage form comprising an active ingredient combination of nifedipine or nisoldipine and at least one angiotensin II antagonist and/or at least one diuretic, characterized in that nifedipine or nisoldipine is released in the body in a controlled (modified) manner and the angiotensin II antagonist and/or the diuretic is released rapidly (immediate release (IR)), and also to processes for their preparation, to their use as medicaments and to their use for the prophylaxis, secondary prophylaxis or treatment of disorders.

Pharmaceutical dosage form comprising nifedipine or nisoldipine and an angiotensin II antagonist and/or a diuretic

The present invention relates to orally administrable multiple-unit sustained-release dose forms having controlled agitation-independent release of active compound and processes for their production using a selected erodable hydrophilic polymer (HPC) and a limitation of the maximum size of the active compound-containing polymer particles to &lE;3 mm.

Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same

This invention relates to an orally administered osmotic drug release system that consists of a shell and a core containing a pharmaceutically active substance, as well as a process for its production. The invention relates further to an osmotic drug release system for use as a drug in human beings and animals, as well as the use of the osmotic drug release system in the production of a drug for the treatment and/or prevention of illnesses in human beings and animals.

Osmotic medicament releasing system

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Solingen, Germany

Erich Brendel