Lonza Inc.

Lonza Ag

Merck & Company, Inc.

Lonza S.p.a.

Erich Armbruster

Josef Heveling

Hans-Joachim Guntherodt

Volker Franzen

Halim Baris

Jean-Paul Roduit

Yves Bessard

James Edward Leresche

David Kuo

Alphons Baiker

Ralf Proplesch

Alfons Baiker

Carlo Fumagalli

Olaf Frei

Angelo Vaccari

Roderick J Chuck

Walter Siegrist

Brian Schwegler

Thuy Quach

Alkis Sofianos

Rosa Lancia

Günther Rosenthal

Lukas Utiger

Hans-Rudolf Dettwiler

Markus Rohner

Acetoacetic acid arylamides are continuously produced from diketene and primary or secondary aromatic amines under the conditions of a reactive distillation in the presence of water. The continuous method provides a high purity of the products, nearly quantitative yields and a high rate of throughput.

Method for producing acetoacetic acid arylamides

A four-step process for preparing 1-(6-methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone of the formula: starting from 2-methyl-5-ethylpyridine. 1-(6-Methylpyridin-3yl)-2-[4-(methylsulfonyl)phenyl]ethanone is an intermediate for preparing inhibitors.

Process for preparing 1-(6-methylpyridin-3-yl)-2-[4- (methylsulphonyl)phenyl]ethanone

A starting product for the preparation of COX-2 inhibitors, notably the compound 1-(6-methylpyridine-3-yl)-2-[(4-(methylsulfonyl)phenyl]ethanone of the formula (I): A method for making the compound.

1-(6-methylpyridine-3-yl)-2-[4-(methylsulphonyl) phenyl] ethanone and method for its preparation

Process for producing methanol and catalyst therefor

A process for preparing nicotinamide, wherein, in the first stage, 2-methyl-1,5-diaminopentane is catalytically converted into 3-picoline, then the 3-picoline is converted via an ammonoxidation into 3-cyanopyridine and, finally, the 3-cyanopyridine is converted microbiologically into the nicotinamide.

Process for preparing nicotinamide

Process for the preparation of 3-methylpiperidine and 3-methylpyridine

Process for the production of gamma-butyrolactone

Catalytically-active metallic glasses containing at least one element from a subgroup of the periodic system and at least one element from a main group of the periodic system. Process for the production of catalytically-active metallic glasses where the metallic glass is produced from at least one element from a subgroup of the periodic system and at least from one element from a main group of the periodic system. The metallic glasses are activated by self-activation or by an oxidative and/or reductive treatment. The catalytically-active metallic glasses can be used as hydration, oxidation or isomerization catalysts.

Process for the production of catalytically-active metallic glasses

Catalytically-active metallic glasses containing at least one element from a subgroup of the periodic system and at least one element from a main group of the periodic system. Process for the production of catalytically-active metallic glasses where the metallic glass is produced from at least one element from a subgroup of the periodic system and at least from one element from a main group of the periodic system. The metallic glasses are activated by self-activation or by an oxidative and/or reductive treatment. The catalytically-active metallic glasses can be used as hydrogenation oxidation or isomerization catalysts.

Catalytically-active metallic glasses containing at least one element from a subgroup of the periodic system and at least one element from a main group of the periodic system. Process for the production of catalytically-active metallic glasses where the metallic glass is produced from at least one element from a subgroup of the periodic system and at least from one element from a main group of the periodic system. The metallic glasses are activated by self-activation or by an oxidative and/or reductive treatment. The catalytically-active metallic glasses can be used as hydrogenation, oxidation or isomerization catalysts.

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Naters, Switzerland

Erich Armbruster