Shifamed Holdings, LLC

Abbott Cardiovascular Systems, Inc.

Parapatch, Inc.

Fox Hollow Technologies, Inc.

Eric Willis

Amr Salahieh

Tom Saul

Claudio Argento

Bob Vaughan

Ali Salahieh

Theodore V Benderev

Cora St Anne

Joseph St Anne

Cindy Santa Cruz

Kevin Wasserstein

Paul M Consigny

William Earl Webler, Jr

Brett Allen Follmer

Florian Ludwig

Stephen W Boyd

Shuji Uemura

Fozan El-Nounou

Geoffrey H Willis

Alfredo Cantu

Peter L Callas

TOm Saul

Mike Stewart

Claudio R Argento

Claudio P Argento

An accommodating intraocular lens (AIOL) for implantation within a capsular bag of a patient's eye comprises first and second components coupled together to define an inner fluid chamber and an outer fluid reservoir. The inner region of the AIOL provides optical power with one or more of the shaped fluid within the inner fluid chamber or the shape of the first or second components. The fluid reservoir comprises a bellows region with one or more folds of the bellows extending circumferentially around an optical axis of the eye. The bellows engages the lens capsule, and a compliant fold region between the inner and outer bellows portions allows the profile of the AIOL to deflect when the eye accommodates for near vision. Fluid transfers between the inner fluid chamber and the outer fluid reservoir to provide optical power changes when the eye accommodates.

Accommodating intraocular lens

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.

An accommodating intraocular lens comprises a first lens component, a second lens component, and an adhesive between portions of the two lens components. The cured adhesive bonds the lens components to form a fluid chamber. The lens components are bonded to one another along a seam which extends circumferentially along at least a portion of the lens components. The lens components may comprise the same polymer material. The cured adhesive also comprises the polymer or a prepolymer of the polymer to provide increased strength. The polymer is hydratable such that the lens components and the cured adhesive therebetween can swell together to inhibit stresses between the lens components and the cured adhesive.

Hydrophilic AIOL with bonding

Systems and methods for neuromodulation of a female patient suffering from a pelvic condition, such as incontinence, are disclosed. A mechanical stimulus such as pressure, tension, traction, friction, or vibration for example can be applied to one, two, or more clitoral structures sufficient to cause a physiologic stimulus or inhibition, such as neuromodulation to treat or prevent the pelvic condition.

Systems and methods for treating female incontinence and pelvic nerve dysfunction

A method is provided including introducing a delivery device through a vessel wall to a treatment site within one of a peri-adventitial space or a pericardium adjacent a coronary blood vessel and delivering a treatment agent through the delivery device. The treatment agent is delivered through the delivery device according to conditions that hydraulically dissect tissue planes within the peri-adventitial space. A kit is provided including a delivery device having a needle to be advanced through one of an epicardium of a heart and a wall of a coronary blood vessel into a peri-adventitial space and a treatment agent comprising particles having an average diameter on the order of 15 microns or more to be delivered through the delivery device into the peri-adventitial space.

Catheter having window and partial balloon covering for dissecting tissue planes and injecting treatment agent to coronary blood vessel

Methods and delivery devices for maximizing injectate dispersion in lesioned tissue using needle-based injection devices are herein disclosed. The delivery devices include injection devices with various needle arrays and/or modified needle tip configurations. The needle tip configurations can include linear, hooked or corkscrew tips and/or multiple circumferential openings.

Needle array devices and methods

Devices, methods, and kits for removing material from a body lumen. The devices and methods may be used in a variety of body lumens, including but not limited to coronary arteries and other blood vessels. In general, the device or catheter has a scoop-shaped cutting blade mounted on a catheter body for removing material from a body lumen. The cutting blade has a cutting edge that travels a curved path about a pivot point of the blade, preferably moving in an outward direction from the catheter body to engage the target material for removal. The scoop-shaped blade has a collection surface located behind the cutting edge to collect material removed from said body lumen. Advantageously, a scoop-shaped cutting blade according to the present invention facilitates material engagement and the collection surface may be used to bring material back into the catheter body as the blade begins to part-off material. The cutting blade is usually mounted to move in an inward direction towards the catheter body after the cutting edge has engaged the material. The cutting blade can also more easily engage occlusive material that is compressed against the body lumen wall.

Apparatus and methods for removing material from a body lumen

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Santa Cruz, CA, United States of America

Eric Willis