Oregon Health & Science University

The United States Government As Represented by the Department of Veterans Affairs

Eric Wan

Rudolph Van Der Merwe

Peter Jacobs

Simon Justin Julier

Dawn Konrad-Martin

Methods and compositions for the non-invasive determination of the concentration of an analyte are provided.

Methods and devices for non-invasive analyte measurement

A method of estimating the navigational state of a system entails acquiring observation data produced by noisy measurement sensors and providing a probabilistic inference system to combine the observation data with prediction values of the system state space model to estimate the navigational state of the system. The probabilistic inference system is implemented to include a realization of a Gaussian approximate random variable propagation technique performing deterministic sampling without analytic derivative calculations. This technique achieves for the navigational state of the system an estimation accuracy that is greater than that achievable with an extended Kalman filter-based probabilistic inference system.

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Hillsboro, OR, United States of America

Eric Wan