University of Utah Research Foundation

Other

Virginia Tech Intellectual Properties Inc

Tufts University

Washington State University

Eric W Schmidt

Peter W Jeffs

Joseph O Falkinham

Brian Hathaway

James T Nelson

Mohamed S Donia

Baldomero M Olivera

Gisela P Concepcion

Roberta O'Connor

Zhenjian Lin

Bailey Miller

Rowena R Antemano

Margo Haygood

Alan Light

Mohamed Samir Donia

In one aspect, the invention relates to cyclopeptides and methods of using the disclosed cyclopeptides to treat bacterial infections due to, for example, Gram-negative pathogens. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Antibacterial cyclopeptides targeting acinetobacter and other gram-negative pathogens

Methods and compositions for preventing and/or treating diseases and conditions caused by certain apicomplexan infections are provided. The methods involve administering/providing to a subject one or more of tartrolon D and E, including isomers thereof. Exemplary apicomplexan infections that are prevented/treated by the compounds of the invention include those caused byand

Methods and compositions for prevention and treatment of Apicomplexan infections

The disclosure provides recombinant cells and methods for producing a ribosomally synthesized and posttranslationally modified peptide (RiPP), as well as RiPP libraries and methods for producing RiPP libraries.

Methods for producing ribosomally synthesized and posttranslationally modified peptides

In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein Ris hydrogen or hydroxyl; wherein Ris hydrogen, a-xylose or &#x3b2;-xylose; and wherein Rand Rare each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. In one aspect, Ris not hydrogen or &#x3b2;-xylose when Ris hydroxyl and Rand Rare together oxygen. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Isolation, identification, and uses of antifungal compounds

In one aspect, the invention relates to compounds having a general structure: and methods of using same to modulate calcium release. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Methods and compositions related to neuroactive thiazoline compounds

Disclosed are compositions and methods for cyclization of polymers such as peptides.

Methods and compositions related to cyclic peptide synthesis

In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein Ris hydrogen or hydroxyl; wherein Ris hydrogen or xylose; and wherein Rand Rare each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Disclosed is a device which is designed to improve the accoustics of a drum. The device has two halves, and it attaches about a hole formed in the drum head. One or both halves have portions which can be flared to a variety of degrees, e.g., 90 degrees, 180 degrees, 360 degrees or more.

Acoustical device for drum

Disclosed are compositions and methods for prenylation of polymers such as peptides.

A wind turbine that is mounted on a corner of a building and has a shaft that extends upward and outward from the corner, where the turbine blades are located, and the resulting rotation of the shaft is used for some power consumption purpose in our outside the building.

Wind turbine

Disclosed is a device for improving the tonal characteristics of a stringed instrument. This has been accomplished using a device that interfaces acoustically with the soundhole. The device inhabits space where sound energy waves tend to interfere and redirects the sound energy out of the soundhole. This prevents distortion and delivers more fullness in sound.

Growing community of inventors

Salt Lake City, UT, United States of America

Eric W Schmidt