Tc1 LLC

Other

Thoratec Corporation

Alcon, Inc.

Sub-q, Incorporated

Applied Medical Resources Corporation

Alcon Research, Ltd.

Parker-hannifin Corporation

Eric T Lee

Daniel I Harjes

John Freddy Hansen

William V Hodges

Onur Dur

Mark Philip Ashby

Yi-Ren Woo

Ethan Falk Petersen

Steven H Reichenbach

Joseph C Stark, Iii

Luis Urquidi

Justin Aaron Callaway

Joseph Stark

Eduardo Chi-Sing

Ian McCutcheon

Stephen G Briana

Steve Reichenbach

Ghazal Anvar Mauro

Charles C Hart

David Gary Eldridge

Kathryn B Frederick

Pieter W C J Le Blanc

Gary P Sorensen

Andrew M Cragg

John Donald Hill

Grace Chuang Liao

Ian Coll McEachern

Peter Andriola

Nichole Mercier

Gionata Valchera

Urim Salltakaj

Gregg D Scheller

Eugene De Juan, Jr

Mikhail Boukhny

Donald L Gadberry

Carine Hoarau

Michael D Morgan

John Nguyen

Jin Woo Park

Michael D Auld

Vincent A Baxter

Terry Harrison Shelley

Carl C Awh

Mark Micklatcher

Patrick S Jensen

George Brody

John Mark Di Paola

Pete Cardamone

Khiun F Tjia

Brad Yin Chen

Sherman George Davis

Chris Eskildsen

John J Hagerty, Jr

Robert Balsamo

Anthony D Cornetto, Iii

Joseph C Stark Iii

Anvar Mauro Ghazal

John Fredrick Hansen

Nichole Rondeau

The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

Pressure sensing ventricular assist devices and methods of use

A wireless power transfer system is provided. The system includes an external transmit resonator and an implantable receive resonator. The transmit resonator is configured to transmit wireless power, wherein the external transmit resonator includes one of i) one or more loops of Litz wire and ii) a plurality of stacked plates. The implantable receive resonator is configured to receive the transmitted wireless power from the external transmit resonator, wherein the implantable receive resonator is configured to power a ventricular assist device (VAD) implanted in a subject using the received wireless power. The implantable receive resonator includes the other of i) the one or more loops of Litz wire and ii) the plurality of stacked plates.

Systems and methods for wireless energy transfer for ventricular assist devices

Certain aspects of the present disclosure provide a surgical cassette configured to engage a first plurality of rollers of a first roller head. The cassette comprises a face coupled to a first substrate, the face being at a first angle with respect to the first roller head's axis of rotation and a wall of first substrate being at a second angle with respect to the axis of rotation, wherein the first angle is different from the second angle. The cassette also comprises a first sheet positioned on the wall's surface, wherein the first sheet and the wall form first one or more pump segments configured to engage the first plurality of rollers in a position where force applied by each one of the first plurality of rollers on the first one or more pump segments has a direction that is not parallel to the first roller head's axis of rotation.

Peristaltic pump

A blood circulation assist system includes a ventricular assist device (VAD) and a controller. The VAD is attachable to a heart of a patient to pump blood from a ventricle of the heart into a blood vessel of the patient. The VAD includes an impeller, a motor stator operable to rotate the impeller, and an accelerometer generating an accelerometer output indicative of accelerations of the VAD. The controller controls operation of the motor stator to control rotational speed of the impeller based on the accelerometer output.

Systems and methods for inertial sensing for VAD diagnostics and closed loop control

The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs.

Communication methods and architecture for heart treatment systems

Systems and methods for performing personalized cardiovascular analyses are provided. A method includes building, using a modeling and simulation computing device, a patient-specific model, storing, using the modeling and simulation computing device, the patient-specific model in a database, receiving, at the modeling and simulation computing device, remote monitoring data from at least one remote monitoring data source, and receiving, at the modeling and simulation computing device, clinical data from at least one clinical data source. The method further includes updating, using the modeling and simulation computing device, the patient-specific model using the remote monitoring data and the clinical data, performing, using the modeling and simulation computing device, at least one simulation on the updated patient-specific model, and outputting, from the modeling and simulation computing device, at least one output based on the at least one simulation.

Systems and methods for personalized cardiovascular analyses

Disclosed herein is an implantable blood pump assembly that includes a housing defining an inlet, an outlet, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path. The blood pump assembly further includes a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet, a stator positioned within the internal compartment and operable to drive the rotor, and an inlet conduit connected to the housing inlet and having a downstream end that has a reduced cross-sectional area that produces a localized region of high velocity blood flow. The blood pump assembly further includes at least one pressure sensor positioned between the inlet and the outlet and configured to detect a pressure of blood flowing through the flow path. The pressure sensor is located adjacent the downstream end of the inlet conduit.

Implantable blood pump assembly including pressure sensor and methods of assembling same

Adjusting pump protocol based on irregular heart rhythm

Blood pump devices having improved rotary seals for sealing a bearing assembly supporting a rotor provided herein. Such rotary seals are particularly suited for use in blood pump devices that include rotors having cantilevered supported through a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The rotary seal can include a first and second face seal that are preloaded with a deflectable compliance member incorporated into the pump housing or a pair of magnets. Such rotary seals can instead or further utilize tight fitment between components or a bio-absorbable fill material to seal an interface between the rotor shaft and pump housing to seal the bearing assembly from fluid flowing through the pump.

Rotary seal for cantilevered rotor pump and methods for axial flow blood pumping

Apparatuses and methods relating to interfacing and controlling external batteries are described. In one embodiment, an external battery is integrated with a touch screen display. In one embodiment, the external battery provides an infrared communication link with a detachable device or system controller. In one embodiment, the external battery touch screen interface provides data received from a detachable device or system controller.

Touch screen interface and infrared communication system integrated into a battery

Systems, methods, and devices for securing a driveline to a bone are disclosed herein. The driveline can connect an external controller to an implantable blood pump. The bone anchor can include a driveline capture portion. The driveline capture portion can receive the driveline and fix a position of the driveline with respect to the driveline capture portion. The driveline capture portion includes: a driveline receiver that can receive the driveline; and a driveline anchor that can engage the driveline to fix the position of the driveline with respect to the driveline receiver. The bone anchor can include a bone capture portion. The bone capture portion can engage a bone and fix a position of the bone with respect to the bone capture portion.

Driveline bone anchors and methods of use

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Oakland, CA, United States of America

Eric T Lee