Proteus Digital Health, Inc.

Alien Technology Corporation

Otsuka Pharmaceutical Company, Limited

Eric Snyder

Hooman Hafezi

Benedict Costello

Timothy Robertson

Robert Duck

Jeremy Frank

Robert Azevedo

Peter Bjeletich

Iliya Pesic

Mark Zdeblick

Olivier K Colliou

Gordon S W Craig

Brad Cozad

Jay Kuang-Jieh Tu

Mark Alfred Hadley

Glenn Wilhelm Gengel

Scott John Herrmann

Susan Swindlehurst

Eric Kanemoto

Ali A Tootoonchi

Lily Liong

Power sources that enable in-body devices, such as implantable and ingestible devices, are provided. Aspects of the in-body power sources of the invention include a solid support, a first high surface area electrode and a second electrode. Embodiments of the in-power sources are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the power sources of the invention.

In-body power source having high surface area electrode

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Communication system with enhanced partial power source and method of manufacturing same

Low profile antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include low profile signal transmission antennas configured such that they are flexible or degrade after use, allowing the antenna and attached components to pass easily through the body. Embodiments of the low profile antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.

Low profile antenna for in body device

The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.

Ingestible circuitry

Identifier circuits for generating unique identifiable indicators and techniques for producing same

RFID antennas for ingestible devices, such as ingestible event markers, are provided. Aspects of the ingestible devices of the invention include RFID signal transmission antennas with a battery that is activated upon being exposed to fluid in the body. Embodiments of the RFID antennas are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.

RFID antenna for in-body device

An electronic assembly. The assembly includes a substrate, a plurality of recessed regions, and a plurality of functional blocks. Each functional block is deposited in one of the recessed regions. A substantial amount of the plurality of functional blocks is recessed below a top surface of the substrate. Substantial amount is defined by any one of less than 10% of said functional blocks protrudes above the top surface of the substrate; less than 1% of the functional blocks protrudes above the top surface of the substrate; more than 90% of the functional blocks are recessed below the top surface of the substrate; or more than 99% of the functional blocks are recessed below the top surface of the substrate.

Assembly comprising functional block deposited therein

An apparatus and methods of making an electronic assembly. The electronic assembly comprises a functional block having at least one asymmetric feature. The functional block comprises an integrated circuitry to perform a function pertaining to the electronic assembly. The electronic assembly further comprises a substrate having a receptor site to mate with the functional block using a fluidic self-assembly process.

Methods and apparatuses relating to block configurations and fluidic self-assembly processes

Apparatus relating to block configurations and fluidic self-assembly processes

Growing community of inventors

South San Francisco, CA, United States of America

Eric Snyder