Imv Technologies

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Université Grenoble Alpes

Swissgenetics

Centre National De La Recherche Scientifique-cnrs

Institut National De La Sante Et De La Recherche Medicale (inserm)

Centre Hospitalier Universitaire Grenoble Alpes

Eric Schmitt

Jean-Charles Gorges

Christian Beau

Christophe Arnoult

Ludovic LeFranc

Olivier Carion

Hélène Guyomar

Agnes Camus

Guillaume Martinez

Philippe Clairaz

Thierry Louviot

Jessica Escoffier

Olivier Couture

Joël Grosos

Pierre Ray

Agnès Camus

Anne Linda Van Kappel-Dufour

Jean-Louis Douesnel

Anne Linda Van Kappel

The straw comprises a tube () and a gas-permeable liquid-tight stopper (), which stopper is disposed in the tube closer to one end () of the tube than another end () of the tube, which tube and which stopper are configured for the stopper to be able to slide in the tube towards the other end (), said tube being transparent or translucent, said stopper comprising an identifier component () configured to emit, when it is illuminated with ultraviolet light, light of which the spectrum comprises at least one peak having a crest of predetermined wavelength in visible light, whereas when it is illuminated by visible light said identifier component does not emit said light of which the spectrum comprises said peak.

Straw for the preservation of a predetermined dose of liquid-based substance

The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.

Method for increasing the lifespan and motility of animal sperm using an inhibitor of Slo3 potassium channel

The invention relates to a straw comprising a tube () and a gas-permeable and liquid-tight stopper (), said stopper () being arranged in the tube (), close to an end (). The invention is characterised in that the stopper () comprises an indicator component () having a first pre-determined colour in the absence of previous contact with said substance () and a second pre-determined colour, of a different shade from that of the first colour, once it has been in contact with said substance (). The assembly comprises the straw () and a device () for controlling the filling of the straw.

Straw for the preservation of a predetermined dose of liquid-based substance, in particular pure or diluted animal semen; and set comprising it

An appliance includes a handle, a speculum tube extending axially from the handle as far as a distal end where it has an opening, a video viewing system having a lens arranged in the speculum tube and a transmission device connected to the lens and connectable to a remote viewing screen, and a lens support for keeping the lens in a predetermined position with respect to the speculum tube, in which position the lens is near the opening and opposite the space situated beyond the opening, characterized in that the speculum tube has an end part and a main part extending between the end part and the handle, the end part being arranged around the support and delimiting the opening, the end part being elastically deformable and the main part being rigid.

Appliance for assisting in vaginal penetration and provided to receive a working tool

A straw includes a tube (), a stopper () arranged in the tube and having a passage () extending through it, and an emptying needle () having a first portion () protruding from the stopper as far as a distal end () situated in the tube, and a second portion () situated in the passage () of the stopper, the needle and the stopper forming an insert () entirely disposed in the tube and having an internal conduit () fluidically connecting the internal spaces of the tube that are situated to either side of the insert, the internal conduit being formed at least in part by the needle. A method for emptying the straw includes establishing a fluidic communication between the needle and a receptacle, and making an opening in the tube in order to connect the dose of liquid-based substance to the atmosphere and allow it to flow.

Straw for cryogenic preservation of a dose of liquid-based substance, assembly comprising same, and method for empty this straw

The invention concerns a cryogenic system () for vitrifying a substance comprising biological material to be preserved in a receiving region of a thin tube (), comprising a tank () containing a bath () of a cryogenic agent and a support member () mounted on said tank in a predetermined first position in which said tube is orientated upright, the receiving region being immersed in a liquid zone () of said bath, and an opening of said tube being situated above said bath, in a zone of ambient air above said bath, in order to introduce the substance into the tube, the support member being mounted on said tank in a second predetermined position, in which said receiving region is immersed in the liquid zone and said opening is situated immediately above said liquid zone, in a gaseous zone () of said bath above said liquid zone and below said zone of ambient air, and being raised from said second position.

System and method for vitrifying a biological substance

A device for preserving a predetermined dose of liquid-based substance, notably animal semen or a preservation medium containing embryos or tissue samples, comprises a tube () made of a weldable plastics material. The tube allows a service state in which a receiving portion () intended to contain the said predetermined dose has a circular cross-section whereas a sealing portion () comprises a welded pinch () and a transition zone (). Over at least part of the sealing portion a differentiating edge region () gives the external surface of the tube a visual appearance different from the visual appearance of the external surface of the tube outside of the differentiating edge region. A range comprises such a device and a similar device but without the differentiating edge region.

Device for preserving a predetermined dose of liquid-based substance, and range of such devices

The device () comprises an inlet element () comprising an interface () for connecting to an artificial vagina and delimiting an inlet opening (), a filter delimiting with the inlet element () an inlet chamber () on the side of the filter turned towards the opening () and a collection bag () extending between a closed end () and an open end () in which said inlet element is engaged; said bag and said filter delimiting a collection chamber () on the side of the filter turned towards the end (); by means of which the semen entering through the opening () passes through the filter and comes to the collection chamber (); the filter being a perforated wall () having a tubular portion () and a bottom portion () closing said tubular portion, and having a surface density of orifices () that is greater on said bottom portion than on said tubular portion.

Device for collecting animal semen

The straw comprises a tube () and a stopper () fixed relative to the tube () and comprising a male connector tip () configured in order that a syringe needle () having a female connector tip () with a frusto-conical internal surface in accordance with a standard can be connected to said stopper () by engagement of the female connector tip () of the needle on the male connector tip () of the stopper (). The injection device comprises such a straw () and a syringe needle (). The method of emptying the straw comprises the step of pushing the dose of liquid-based substance () packaged in the straw () towards the stopper ().

Straw for the preservation of a predetermined dose of liquid-based substance, as well as a method and injection device that employ it

The invention relates to a storage receptacle () with a longitudinal opening () through which straws () for packing liquid-based substance are passed in a predetermined orientation of the straws, a housing () provided for the straws and configured to be inserted slidably in a cover () of the receptacle, the latter having an open configuration, in which the housing is partially inserted in the cover and the opening is free for the passage of the straws, and a closure configuration, in which the housing is inserted in the cover and the opening is closed by the cover in order to prohibit the passage of the straws. The housing has a parallelepipedal shape, a first front wall in which the opening is formed, a first bottom wall, two first longitudinal wails extending parallel to the opening, and two first side walls which each have two diagonals of a length less than or equal to the length of the straws.

Storage receptacle for straws for packaging animal semen and processing installation comprising such a receptacle

The present invention relates to a composition for use in low dose artificial insemination and to a process for artificial insemination of a female mammal using a dose of sperm originating from a male mammal of the same species that is significantly lower than necessary in the absence of the composition. The preferred female mammal is a sow (), and preferably the composition is for use in artificial uterine insemination, and the process for artificial insemination preferably is uterine insemination.

Process and composition for low dose insemination

The straw includes a tube () extending between a first end () and a second end () and includes a gas-permeable but liquid-impermeable plug (). The tube () is made of a thermochromic material that reversibly changes colour at a pre-set temperature threshold, by virtue of which colour change the tube () has a first visual appearance if the temperature thereof is below the preset threshold and a second visual appearance that is different from the first visual appearance if the temperature thereof is above the preset threshold.

The invention relates to a La-1-like peptide agent that increases sperm motility. It is non-toxic and it may be used to treat male infertility in humans, and also to increase fertility in animals. It may be used in artificial reproductive techniques such as in vitro fertilisation (IVF), including intra-cytoplasmic sperm injection (ICSI). The La-1 like peptide agent may also be used in artificial insemination techniques such as intra-cytoplasmic uterine injection (IUI).

Use of La1-like peptide isolated from maurus palmatus venom as an activator of sperm motility in mammals

The installation () comprises a treatment machine () and a supply and positioning device () configured to receive the straws () and dispose them one by one in a predetermined orientation for their treatment by said machine. The device () comprises a curved ramp () having a reception portion () for the straws () and an ejection portion () for the straws, the ramp being configured to convey, to the ejection portion (), a straw () received on the reception portion () and sliding on the ramp (), the ramp having a concave profile such that said profile has an orientation closer to the vertical in the reception portion () than in the ejection portion (), such that a straw received on the reception portion () is accelerated to the ejection portion () at which the straw is guided and ejected with a predetermined orientation.

Treatment installation for straws for packaging animal semen, comprising a supply and positioning device for said straws

The container straw comprises a tube () and a stopper () that is permeable to gasses and impermeable to liquids, which stopper () is arranged in the tube () near one end (), characterized in that it comprises an indicator component () configured to emit, at least when the container straw () is full, light the spectrum of which contains at least one spike having a peak of predetermined wavelength. The assembly comprises the container straw () and a container straw recognition device ().

Growing community of inventors

Villaines-la-Juhel, France

Eric Schmitt