Heska Corporation

Colorado State University Research Foundation

Cedus, Inc.

Eric R Weber

Catherine A McCall

Shirley Wu Hunter

Glenn R Frank

Keith E Rushlow

Donald L Wassom

James P Porter

Torrance M Nett

Lynda Wallenfels

Shumin Yang

Gek-Kee Sim

The present invention provides novel, modified pokeweed antiviral proteins, nucleic acids that encode the proteins, conjugates that incorporate the proteins, and methods to make and use the proteins. The present invention also provides methods to administer the conjugates to animals, for the purpose of directing toxin to particular cells.

Recombinant pokeweed antiviral proteins, compositions and methods related thereto

The present invention relates to high molecular weightproteins, nucleic acid molecules encoding such proteins, and therapeutic and diagnostic reagents derived from such proteins.

Dermatophagoides nucleic acid molecules

The invention relates to: nucleic acid molecules encoding the light chain and heavy chain of feline immunoglobulin E (IgE), including species-specific regions of feline IgE; proteins encoded by the nucleic acid molecules; inhibitors to the nucleic acids and proteins; antibodies to the proteins; cells transformed with the nucleic acid molecules; assays employing the transformed cells, nucleic acids, antibodies and/or proteins or portions thereof; methods for treating IgE-mediated responses (ie. allergy) using the materials provided; methods for eliciting an immune response to IgE and kits containing the nucleic acid molecules, proteins or derivatives thereof (ie. antibodies).

Feline immunoglobulin E molecules and related methods

The present invention relates to canine interleukin-5 proteins; canine interleukin-5 nucleic acid molecules, including those that encode canine interleukin-5 proteins; to antibodies raised against such proteins; and to inhibitory compounds that regulate such proteins. The present invention also includes methods to identify and obtain such proteins, nucleic acid molecules, antibodies, and inhibitory compounds. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to regulate an immune response in an animal.

Canine IL-5 proteins and fragments thereof

Dermatophagoides proteins and uses thereof

The present invention relates to equine Fc epsilon receptor alpha chain nucleic acid molecules, proteins encoded by such nucleic acid molecules, antibodies raised against such proteins, and inhibitors of such proteins. The present invention also includes methods to detect IgE using such proteins and antibodies. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies and/or inhibitory compounds as well as the use of such therapeutic compositions to mediate Fc epsilon receptor-mediated biological responses.

Equine Fc epsilon receptor alpha protein

Cannie IL-5 nucleic acid molecules

Feline immunoglobulin E proteins and compositions thereof

Dermatophagoides proteins and fragments thereof

Anti-equine Fc epsilon receptor alpha chain antibodies and methods to detect IgE

Equine Fc epsilon receptor alpha chain proteins and uses thereof

The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention also relates to ectoparasite saliva proteins, nucleic acid molecules having sequences that encode such proteins, and antibodies raised against such proteins. The present invention also includes methods to obtain such proteins and to use such proteins to identify animals susceptible to or having allergic dermatitis. The present invention also includes therapeutic compositions comprising such proteins and their use to treat animals susceptible to or having allergic dermatitis.

Ectoparasite saliva proteins and apparatus to collect such proteins

Feline immunoglobulin E molecules and compositions there of

Growing community of inventors

Fort Collins, CO, United States of America

Eric R Weber