Beckman Coulter, Inc.

Coulter International Corp.

Eric Malcolm Grace

Thys Müller

Bart Jan Wanders

Jiuliu Lu

Jing Li

William Weigong Li

Rongchang Xin

Ted W Britton

Santos E Vargas

Min Zheng

Shuliang Zhang

Maritza Lavernia

Thys Mueller

William Li

A sampling system that includes a traverse, a sample aspiration module body, and a mechanical system. The sample aspiration module body is configured to travel along the traverse. The mechanical system is configured to move the traverse from a first position to a second position, wherein both the first position and the second position lie in the same plane.

Sampling system

Display screen of a diagnostic device with graphical user interface

Diagnostic device

A method of correction of particle interference to hemoglobin measurement of a blood sample on a hematology analyzer is provided. The method includes mixing an aliquot of a blood sample with a lytic reagent to lyse red blood cells and forming a sample mixture; measuring absorbance of the sample mixture at a predetermined wavelength of a hemoglobin chromogen formed in the sample mixture, and obtaining an apparent hemoglobin concentration of the blood sample using obtained absorbance; measuring concentration and size of cellular particles remaining in the sample mixture; removing contribution of the cellular particles to the apparent hemoglobin concentration using the concentration and the size of the cellular particles to obtain a corrected hemoglobin concentration of the blood sample; and reporting the corrected hemoglobin concentration of the blood sample.

Method of correction of particle interference to hemoglobin measurement

A method for preventing either the introduction of air into a liquid aspirated from a container through an aspiration line passing through a container cap, or the over-filling or non-filling of a container by a liquid dispensed through a dispensing line passing through a container cap. Such method comprises the steps of simultaneously detecting that (a) the container cap is properly positioned on and secured to a liquid container from which liquid is to be aspirated, or into which a liquid is to be dispensed, and (b) detecting that the level of liquid in the container is either above or below a predetermined level.

Fail-safe method and apparatus for aspirating and/or dispensing liquids in automated laboratory instruments

A method for analyzing an abnormal particle population in an experimental sample containing particles involves a particle property distribution index based on an average particle property (e.g., size) distribution curve for multiple normal samples in a particle analysis instrument. The process involves producing an experimental particle property distribution curve by analyzing an experimental sample containing particles in the instrument. The distribution curve of the experimental sample is analyzed to identify particle populations at the lower or upper region of the experimental distribution curve that differ from particle populations in the regions of an average particle property distribution curve. Thereafter, the number of particles within the lower or upper region of the experimental distribution curve that differs from the average curve is determined and employed for diagnosis of a relevant characteristic of the particle population. A computer program which makes calculations for such methods can be employed or can be integrated into a particle analysis instrument. The method, program, and instruments of this invention provide a novel red blood cell parameter.

Method for the analysis of abnormal particle populations

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Cooper City, FL, United States of America

Eric Malcolm Grace