Novartis Ag

Other

Novartis Pharma Gmbh

Recordati Ag

Eric M Loeser

Prasad Koteswara Kapa

Paul Allen Sutton

Augustus O Okhamafe

Piotr Henryk Karpinski

Michael John Girgis

Ahmad Hashash

Werner Zaugg

Rampurna Gullapalli

Kangwen L Lin

Guang-Pei Chen

Ulrich Beutler

Eduardo Sy

Mahavir Prashad

Frederick Ray Kinder, Jr

Joel Slade

Xinglong Jiang

George Tien-San Lee

Brian F Mulrine

The invention relates to a phosphate salt or a nitrate salt of 4-(R)-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-5-yl-3-fluoro-benzonitrile, especially in crystalline form, and specific forms of these salts, as well as related invention embodiments. The salts and salt forms allow for the prophylactic and/or therapeutic treatment of aldosterone synthase and/or aromatase mediated diseases or disorders.

Forms and salts of a dihydropyrrolo[1,2c]imidazolyl aldosterone synthase or aromatase inhibitor

Salts of benzimidazolyl pyridyl ethers are provided, particularly salts of {1-methyl-5-[2-(5-trifluoromethyl-1H-imidazol-2-yl)-pyridin-4-yloxy]-1H-benzoimidazol-2-yl}-(4-trifluoromethyl-phenyl)amine. Compositions and formulations including such salts and surfactants as well as methods of preparing such compositions and formulations are provided.

Salts of benzimidazolyl pyridyl ethers and formulations thereof

The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use &#x3b1; &#x3b2;-lactarn intermediate. Certain optically pure intermediates are also claimed.

Process for preparing N-hydroxyformamido-propyl pyrrolidin compounds and intermediates

A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.

Process for the manufacture of organic compounds

The present invention relates to certain salts of discodermolide acid, pharmaceutical compositions containing said salts, the use of said salts in treating tumors and to a process for making said salts.

Certain salts of discodermolide acid, pharmaceutical compositions containing them and their use in treating tumors

This disclosure refers to the securing of lenses in an ophthalmic mounting having a split rim eyewire using a spring loaded connecting device.

Eyewire locking device

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Scotch Plains, NJ, United States of America

Eric M Loeser