Vertex Pharmaceuticals, Inc.

Eric L Haseltine

Weichao George Chen

Samuel Moskowitz

Sarah Robertson

David Waltz

Eleni Dokou

Varsha Dhamankar

Beili Zhang

Lori Ann Ferris

Kirk Raymond Dinehart

Katie McCarty

Nishanth Gopinathan

Catherine Metzler

Nitin Nair

Porntula Panorchan

Patrick Sosnay

Cathy Chu

Bartlomiej Borek

Rudy Gunawan

Katie Mccarty

Welchao George Chen

Compound I of the formula and/or pharmaceutically acceptable salt(s) of Compound I comprised in a pharmaceutical composition and methods of using the same to treat cystic fibrosis.

Methods of treatment for cystic fibrosis

This application describes methods of treating cystic fibrosis or a CFTR mediated disease comprising administering Compound I or a pharmaceutically acceptable salt thereof. The application also describes pharmaceutical compositions comprising Compound I or a pharmaceutically acceptable salt thereof and optionally comprising one or more additional CFTR modulating agents.

Compound I of the formula (I) and/or pharmaceutically acceptable salt(s) of Compound I comprised in a pharmaceutical composition and methods of using the same to treat cystic fibrosis. 

Compound I of the formula (formula) A pharmaceutically acceptable salt of Compound I. Pharmaceutical compositions containing at least Compound I and methods of treating cystic fibrosis comprising administering at least Compound I. Pharmaceutical compositions containing a pharmaceutically acceptable salt of at least Compound I and methods of treating cystic fibrosis comprising administering a pharmaceutically acceptable salt of at least Compound I. 

A pharmaceutical composition comprising Compound I: Methods of treating cystic fibrosis comprising administering one or more of such pharmaceutical compositions to a patient.

Pharmaceutical compositions for treating cystic fibrosis

Crystalline Forms of Compound I: and pharmaceutically acceptable salts thereof are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Crystalline forms and compositions of CFTR modulators

Growing community of inventors

Melrose, MA, United States of America

Eric L Haseltine