Ge Healthcare Limited

Ge Healthcare Limited Company

Eric Horn

Dimitrios Mantzilas

Steven Michael Fairway

Nigel Anthony Powell

Julian Grigg

Imtiaz Ahmed Khan

Torild Wickstrom

Nigel John Osborn

Jonathan Robert Shales

Gry Helene Olaussen

Methods and devices for directing a waste fluid from a radiopharmaceutical synthesis system to a waste vessel are provided. In one example, the method includes serially connecting a primary waste vessel to a secondary waste vessel with a fluid conduit, including a waste valve connected to the fluid conduit extending between the primary waste vessel and secondary waste vessel; opening the waste valve so as to allow fluid communication between cavities of the primary and secondary waste vessels; drawing a low pressure in both waste vessels; closing the waste valve so as to fluidically isolate the secondary waste vessel from the primary waste vessel, discharging the waste fluid through a pump valve into the primary waste vessel, and opening the waste valve to evacuate the waste fluid from the primary waste vessel into the secondary waste vessel.

Methods and systems for emptying a waste vessel

A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol (F) Injection for the imaging of &#x3b2;-amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [F]flutemetamol by means of solid phase extraction (SPE).

Purification method

The present invention provides a method to prepare anF-labelled tricyclic indole compound comprising a solid-phase extraction (SPE) purification step. This method is particularly suitable for carrying out the radiofluorination method on an automated synthesizer. In addition to the radiofluorination method, the present invention provides a cassette designed to carry out the method on an automated synthesizer.

Solid phase extraction method

A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol (18F) Injection for the imaging of b amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [18F]flutemetamol by means of solid phase extraction (SPE).

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Buckinghamshire, United Kingdom

Eric Horn