Case Western Reserve University

Cleveland State University

Marval Pharma, Inc.

Marval Biosciences, Inc.

Eric Hoffman

Ananth V Annapragada

Ravi Bellamkonda

Chen-Yu Kao

Chandra Vijayalakshmi

Ananth Annapragada

Ravi V Bellamkonda

Ketan Ghaghada

Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided. Example pharmaceutical compositions of such liposomes, when administered to a subject, provide for increased contrast of extended duration, as measured by computed tomography, in the bloodstream and other tissues of the subject. Also provided are example methods for making the liposomes containing high concentrations of contrast-enhancing agents, and example methods for using the compositions.

Compositions and methods for enhancing contrast in imaging

Growing community of inventors

Iowa City, IA, United States of America

Eric Hoffman