Boise State University

Eric Hayden

Steven Burden

Nicholas Shults

Esteban Palencia Hurtado

Stephanie F Hudon

Disclosed herein are methods of determining telomere length using universal reference primers. The reference primer pairs efficiently and reproducibly amplify genomic DNA in any vertebrate species. Kits for determining the length of telomeres or others repetitive regions in a sample are also provided.

Methods and compositions for assaying repetitive sequences

The present disclosure relates to oligonucleotide biosensors that bind to a fluorophore through a reporter domain and to one or more target ligand(s) through one or more target domain(s), which is connected to the reporter domain through one or more linker domain(s). The binding of the target ligand to the target domain affects the fluorescence of the fluorophore when excited by the appropriate wavelength of energy, either by causing dimming or allosteric fluorescence. Methods of selecting biosensors and their use to detect target ligands are also described.

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Boise, ID, United States of America

Eric Hayden