Cardinal Health 414, LLC

Becton Dickinson and Company Limited

Eli Lilly and Company

Battelle Memorial Institute

Philip Morris USA Inc.

Ic Surgical, Inc.

Hypoguard USA Inc.

Veressa Medical, Inc.

Philip Morris Products S.a.

Eric Hassenpflug

Scott Nicholas Danhof

James A Prescott

Mehmet Husnu

Dennis Eshima

Derrick Alcaide

William Godwin Atterbury

David Arthur Holley

James B Gleeson

Chad Edward Bouton

Herman P Benecke

Thomas D Haubert

Daniel B Garbark

Frank E Martin

Vincent J Sullivan

Thomas Alan Klausing

Matthew S Ferriter

Steven Michael Madland

Brian Charles Kelley

Michael Scott Ulrich

Joseph Edward Zambanini

Jeffrey Taylor Stroup

James Stone

Henry Padgett

Robert K Deckman

Michael Anthony Lorenz

Alessandro Egidio Pizzochero

Steven E Wilder

Jeffrey L Ellis

John P Tallarico

Michael S Labbe

John Bartholomew

Jeff Weisgarber

Mark Lafever

Corrie Bennison

James A Woodard, Jr

Tracy L Cameron

Jeffrey Richard Held

Thomas A Pettenski

Christopher Paul McKenzie

Alexandru Campean

Steven R Nelson

Ludwin M Mora

Ryan Somogye

Benjamin M Bartilson

Eric R Navin

Russell Kittel

Maekele Gebrekidan

Steven E Huckaby

Stephen C Schmitt

Benjamin A Tranchina

Mark Wood

James Leamon

Steve Wilder

Muzaffer Yalgin Ozsecen

Mohsin Zafar

John F Jemionek

Ludwin Mora

Larry K Hooks, Jr

Jeffrey Held

Cory Baker

Timothy Blum

Lawrence A Weinstein

Larry Keith Hooks, Jr

Michael Ko

Jane O'Loughlin

Jim Gleeson

Jim Prescott

Arthur Neal Owens, Jr

David A Fingerhuth

William Atterbury

Michael Lorenz

A valve for permitting mixing of at least two components within a barrel is provided including a stopper configured for slidable liquid-tight engagement with an inner surface of the barrel. The stopper is moveable between a first position and a second position and includes a proximal end, a distal end, and a channel extending therebetween. The valve further includes a stationary body comprising a base and a stem, the stem being disposed within the channel of the stopper when the stopper is in the second position. When the stopper is in the first position, there is a liquid-tight seal in the channel, such that fluid flow through the channel is prevented. Movement of the stopper to the second position terminates the liquid-tight seal, thereby establishing fluid communication through the channel. A drug containing device and assembly for delivering a reconstituted drug are also provided herein.

Valve permitting mixing in a drug delivery device

A fluid delivery device has a syringe barrel-type reservoir with plunger, and plunger driver assembly comprising double-acting, telescoping lead screws that is located behind and outside of the barrel. Simultaneously and counter-rotating sleeve screw and center screw telescope out of a nested configuration of the plunger driver assembly and into the reservoir at a rate of double their individual and equal pitch and lead parameters when the sleeve screw is rotated. A threaded nut and gear anchor disposed on an end of the barrel receive the sleeve screw and the threaded nut causes the sleeve screw to translate and rotate in response to motor operation. A distal end of the center screw can be keyed to a plunger pusher for anti-rotation constraint when the motor is imparting rotation on the threaded nut and sleeve screw.

Double-acting, telescoping screw-driven pump mechanism disposed externally to reservoir in fluid delivery device

Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control.

Systems, methods and devices for producing, manufacturing and control of radiopharmaceuticals

An aerosol delivery system, which includes an aerosol delivery unit, the aerosol delivery unit including: a cartridge receiver, which is configured to receive a cartridge assembly; and an inductor configured to receive the cartridge assembly and heat a liquid formulation within a capillary tube to produce an aerosol by induction heating. The cartridge assembly including an active part of the cartridge assembly including a capillary tube; a susceptor, the susceptor configured to partially surround the capillary tube; and a pair of displaceable covers, which surround at least the capillary tube and the susceptor.

Aerosol delivery system

Devices and systems disclosed herein may include a negative pressure pump that includes a reservoir defining a lumen and a longitudinal axis, a piston, and a drive assembly comprising a spring. Motion of the spring may move the piston along the longitudinal axis of the reservoir to create a negative pressure within the reservoir. Methods of manufacturing a negative pressure pump and using a negative pressure pump to remove fluid from a target site are also described.

Negative pressure pumps and related methods

A puller assembly for removing a shield from around a needle of a syringe. The puller assembly includes a grip component and a cap. The grip component has a tubular body defining an interior hollow which axially receives the shield. The tubular body has a slit that allows it to be forcibly shifted from a first arrangement to a second arrangement to change the size of the interior hollow. The tubular body includes a radial inner face with at least one radial inward projection for directly engaging the shield. The cap is grippable by a user. The grip component is held by the cap when inserted within a cavity of the cap during manufacturing installation, and when so held at least one radial inward projection of the grip component engages the shield for removal of the shield from around the needle when the cap is moved. A method of mounting a puller assembly to a shield around a needle is also disclosed.

Needle shield puller cap assembly

Methods, devices and systems for improving pelvic floor dysfunction in a patient suffering therefrom by electrically modulating neural tissue in a minimally invasive fashion using an electrical microstimulator are provided. Methods include inserting an electrical microstimulator having a re-deployable fixation member through skin of a patient's leg and advancing the electrical microstimulator through the skin along tissue of a surgical pathway to an area of the patient's leg. A target implant site can be identified that is above deep fascia and below the skin and that is adjacent to a target nerve associated with pelvic floor function. The electrical microstimulator can be anchored to the target implant site via the re-deployable fixation member or re-positioned, if necessary. A therapy electrical signal can be delivered to the target nerve from the target implant site.

Devices, systems, and methods for improving pelvic floor dysfunction

A closed path vial fill system includes a bulk product vial, a peristaltic pump operated by a stepper motor, a dispensing manifold assembly to which may be coupled at least one final product vial, an optional quality check station, and an optional waste collection system. A concentration, activity, and volume (CAV) sensor may be incorporated into the system to receive a radiopharmaceutical product directly from a synthesizing unit. A control system may be integrated into the system to provide automated control of various aspects of the radiopharmaceutical dispensing process. The system is used to aseptically dispense finished radiopharmaceuticals into receiving vessels, such as a Quality Control vial, a sterility vial, and/or final product vials, while providing users an efficient means for removing and discarding contaminated disposable components.

Closed vial fill system for aseptic dispensing

A valve () for permitting mixing of at least two components within a barrel () is provided including a stopper () configured for slidable liquid-tight engagement with an inner surface () of the barrel. The stopper is moveable between a first position and a second position and includes a proximal end (), a distal end (), and a channel () extending therebetween. The valve further includes a stationary body () comprising a base () and a stem (), the stem being disposed within the channel of the stopper when the stopper is in the second position. When the stopper is in the first position, there is a liquid-tight seal in the channel, such that fluid flow through the channel is prevented. Movement of the stopper to the second position terminates the liquid-tight seal, thereby establishing fluid communication through the channel. A drug containing device and assembly for delivering a reconstituted drug are also provided herein.

A hypodermic syringe includes a barrel with a plunger slidably extending therein. The plunger includes an outer plunger element and an inner plunger element telescoping together. A plunger cap may be advanced after injection to rotate the plunger. A resistance lock retains the cap and plunger indexed until actuation. The rotation actuates latches and locking fingers on the luer hub to engage a probe axially and rotationally on the seal end of the plunger and disengage the slots in the barrel, respectively. The rotation disengages the seal stop to release the annular seal and finally releases the engagement between the outer plunger element and inner plunger element. The foregoing provides for the retraction of the luer hub and associated needle into the barrel.

Retractable hypodermic syringe

A urine specimen container is disclosed which includes multiple urine holding chambers and further includes a cap to be secured to the container that enables extraction of a portion of the urine specimen from one chamber within the container without contaminating the urine specimen contained in an adjacent chamber of the same container.

Multi-chambered urine specimen container for automatic extraction and

Growing community of inventors

Westerville, OH, United States of America

Eric Hassenpflug