Gruenenthal Gmbh

Grunenthal Gmbh

Lts Lohmann Therapie-Systeme Ag

Eric Galia

Lutz Barnscheid

Johannes Bartholomäus

Sebastian Schwier

Johannes Heinrich Bartholomaeus

Elisabeth Arkenau-Maric

Ulrike Bertram

Anne Faure

Anja Geissler

Filip René Irena Kiekens

Eugeen Marie Jozef Jans

Michael Horstmann

Heinrich Kugelmann

Iris Ziegler

Jody Firmin Marceline Voorspoels

Marc Frevel

Kornelia Griessmann

René Eifler

Patrick Mohr

Rod L Hartwig

Jana Pätz

Ingo Friedrich

Regine Kaufmann

Armin Breitenbach

Jan Stampfuss

Anja Geißler

Sebastian Braun

Andrea Schüssele

Wolfgang Prange

Stefan Buller

Eugeen Marie Jans

Klaus Pusecker

Susanne Stoelben

Julia Baronsky-Probst

Richard Fuhrherr

Andrea Schüessele

Olaf Will

Michael Gautrois

Enrique R Pernas

Lars Prenner

Jody Firmin Voorspoels

Filip Rene Kiekens

Andrea Schuessele

A thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising

Oxidation-stabilized tamper-resistant dosage form

The invention relates to transdermal therapeutic systems (TTS) which include, as active ingredient, the NMDA receptor antagonist memantine or one of its physiologically compatible salts. The TTSs can be produced and used for treating diseases of the central nervous system.

Transdermal administration of memantine

The invention relates to a hot-melt extruded pharmaceutical dosage form with controlled release of a pharmacologically active ingredient (A) embedded in a matrix comprising a polymer (C), the dosage form exhibiting a breaking strength of at least 300 N and having an oblong shape comprising a longitudinal direction of extension, a transversal direction of extension orthogonal to the longitudinal direction of extension, a front side, an opposite back side and a circumferential rim between said front and back side; wherein 

Hot-melt extruded pharmaceutical dosage form

A thermoformed, tamper-resistant pharmaceutical dosage form comprises: When the pharmacologically active ingredient is effective against pain, the pharmaceutical dosage form may be used in a method of treating pain. When the pharmacologically active ingredient has abuse potential, the pharmaceutical dosage form may be used in a method of reducing the incidence of the abuse of said pharmacologically active ingredient.

Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc

The invention relates to a pharmaceutical dosage form, preferably with controlled release of a pharmacologically active compound (A) contained therein, the pharmaceutical dosage form very preferably being tamper-resistant and most preferably having a breaking strength Bof at least 500 N in direction of extension Eand having a breaking strength Bof less than 500 N in direction of extension E.

Pharmaceutical dosage form

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Aachen, Germany

Eric Galia