The Cleveland Clinic Foundation

Eric E Roselli

Kelly B Emerton

Douglas R Johnston

Justin Metcalf

Brandon Gulker

Ryan S Klatte

Mark S Lobosky

Daniel J Boffa

John Robert Mehall

David Nagle

David P Mason

Bruce W Lytle

Mark Howell

An endovascular graft including a stent graft and a surgical graft is provided. The stent graft can include an elongated body having a collapsed and expanded configuration and include a frame structure covered by a compression sleeve that retains the elongated body in the collapsed configuration until deployment of the stent graft. The endovascular graft can include a first cuff member sized and dimensioned to extend into a lumen of an aortic arch branch vessel when the endovascular graft is implanted in a subject. The frame structure can include a backstop sized and dimensioned to extend into the first cuff member when the endovascular graft is implanted in the subject. The surgical graft can be partially attached to the stent graft at a proximal end portion thereof.

Endovascular grafts and methods for extended aortic repair

A tubular first device segment has longitudinally spaced proximal and distal first segment ends. The first device segment includes a first segment lumen. A tubular second device segment has longitudinally spaced proximal and distal second segment ends and a second segment lumen. A tubular eversion structure is located longitudinally intermediate the first and second device segments. The eversion structure has longitudinally spaced proximal and distal eversion ends separated by a tubular eversion structure wall. One of the proximal and distal eversion ends is attached to the first device segment and the other of the proximal and distal eversion ends is attached to the second device segment. At least a portion of the eversion structure wall is configured for selective intussusception into at least one of the first segment lumen, the second segment lumen, and another portion of the eversion structure wall.

Method and apparatus for time-differential deployment of an endovascular device within a body lumen

An implantable expandable device includes an occluding surface oriented substantially in a transverse plane. The occluding surface is bounded by a lateral occluding surface edge and a medial occluding surface edge. The occluding surface has an occluding surface body located transversely between the lateral and medial occluding surface edges. A supporting structure is located entirely inferiorly to the occluding surface. The supporting surface includes a plurality of struts extending substantially in the superior-inferior direction. At least a first one of the struts is a full-height strut and spans substantially a full superior-inferior height of the device. At least a second one of the struts is a reduced-height strut and spans substantially less than a full superior-inferior height of the device. The occluding surface substantially occludes a transverse cross-section of the false lumen to substantially block bloodflow in the superior-inferior direction within the false lumen.

Method and apparatus for substantially blocking bloodflow through a dissected aorta

An apparatus for repairing the function of a diseased valve includes a tubular first support member which is expandable to a first average diameter and has oppositely disposed proximal and distal first support member ends. A tubular second support member is spaced axially apart from the first support member and is expandable to a second average diameter that is smaller than the first average diameter. The second support member has oppositely disposed proximal and distal second support member ends. A tubular graft section interconnects the first and second support members and has oppositely disposed proximal and distal graft section ends axially spaced apart by a graft section body. The proximal graft section end is connected directly to the distal first support member end and the distal graft section end is connected directly to the proximal second support member end.

Apparatus and method for repairing the function of a diseased valve

One aspect of the present disclosure can include a frame structure adapted for use with a stent graft. The frame structure can include a scallop region and a Z-form region. The scallop region can have a first end portion, a second end portion, and a perimeter that defines an aperture. The Z-form region can extend from the scallop region and include a plurality of Z-shaped struts, each of which has a first end and a second end that is connected to the scallop region at different points so as to form a central frame structure lumen. The second end portion of the scallop region can include a backstop that is deployable from a first flattened configuration to a second erect configuration. The backstop, in the second erect configuration, is sized and dimensioned to extend into a lumen of an aortic branch vessel.

Frame structures, stent grafts incorporating the same, and methods for extended aortic repair

A staple clip for providing an attachment function in a surgical procedure is described. A center hub has a center hub aperture. The center hub defines a lateral hub plane. A plurality of joining legs each has an inner leg end attached to the center hub and an outer foot defining a lateral foot plane. The inner leg end and outer foot are separated along the leg by an elongate leg body extending laterally outward and longitudinally downward from the center hub. A plurality of lobe pads are attached to the center hub and lie substantially within the lateral hub plane. The inner leg ends and lobe pads alternate with each other around a periphery of the center hub.

Growing community of inventors

Rocky River, OH, United States of America

Eric E Roselli