Leland Stanford Junior University

Eric Cocker

Mark Jacob Schnitzer

Kunal Ghosh

Tatt Wei Ho

Laurie D Burns

Abbas A El Gamal

Benjamin A Flusberg

Juergen Claus Jung

Abbas El Gamal

Erik Paul Anderson

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mmand to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.

Microscopy imaging device with advanced imaging properties

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mmand to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 &#x3bc;m resolution for an image of the field of view.

Analysis of live beings is facilitated. According to an example embodiment of the present invention, a light-directing arrangement such as an endoscope is mounted to a live being. Optics in the light-directing arrangement are implemented to pass source light (e.g., laser excitation light) into the live being, and to pass light from the live being for detection thereof. The light from the live being may include, for example, photons emitted in response to the laser excitation light (i.e., fluoresced). The detected light is then used to detect a characteristic of the live being.

Live being optical analysis system and approach

Imaging, testing and/or analysis of subjects is facilitated with a micro-mirror-based access approach. According to an example embodiment, a micro-mirror is implemented to direct light to a live being such as a biological specimen or a living being. Light from the live being is detected and implemented for use in analyzing the live being. In certain applications, the micro-mirror is fastened to a live being, such as to a skull of a live mouse, while the live being is allowed to move in an unanesthetized state. Behavior of the live being and detected response from the live being are concurrently used to analyze the live being.

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Palo Alto, CA, United States of America

Eric Cocker